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N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide

N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide Structure
CAS No.
503610-43-3
Chemical Name:
N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide
Synonyms
Rosuvastatin EP Imp D;Rsosuvastatin Lactone;Rosuvastatin calcium-5;Rosuvastatin-5S-lactone;Rosuvastatin Lactone-d3;Rosuvastatin-5R-lactone;Rosuvastatin Impurity D;Rosuvastatin EP Impurity D;Rosuvastatin lactone, >=98%;(3R,5R)-Rosuvastatin Lactone
CBNumber:
CB52484896
Molecular Formula:
C22H26FN3O5S
Molecular Weight:
463.52
MOL File:
503610-43-3.mol
MSDS File:
SDS
Modify Date:
2025/1/27 9:38:02
Request For Quotation

N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide Properties

Melting point 131 °C
Boiling point 695.0±65.0 °C(Predicted)
Density 1.387
storage temp. -20°C Freezer
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka 13.22±0.40(Predicted)
color White to Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H319-H335-H315
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
NFPA 704
0
2 0

N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

An isomer of Rosuvastatin Lactone (R700500); intermediate in the production of Rosuvastatin (R700500) derivatives.

N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide Preparation Products And Raw materials

Raw materials

Preparation Products

N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide Suppliers

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503610-43-3(N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide)Related Search:

Rosuvastatin EP Impurity E (Calcium Salt) Pitavastatin Impurity 8 Rosuvastatin Impurity 14 (3R,5R)-Rosuvastatin N-DESMETHYL ROSUVASTATIN-D3
Rosuvastatin (3S,5R)-Rosuvastatin Methyl Ester Rosuvastatin IMpurity (5-Oxo Rosuvastatin tert-Butyl Ester) Rosuvastatin Anhydro Lactone Rosuvastatin IsoaMy Ester
Rosuvastatin EP impurity A (3S,5R)-Rosuvastatin Rosuvastatin methyl ester tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate 4-(4-Fluorophenyl)-6-isopropyl-2-[(N-methyl-n-methylsulfonyl)amino]pyrimidine-5-yl-methanol
3-Oxo Rosuvastatin SodiuM Salt Rosuvastatin ethyl ester Rosuvastatin EP impurity H
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N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide Rosuvastatin-5S-lactone (3R,5R)-Rosuvastatin Lactone Rosuvastatin Lactone-d3 N-[4-(4-Fluorophenyl)-6-(1-Methylethyl)-5-[(1E)-2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyriMidinyl]-N-Methyl-MethanesulfonaMide Rosuvastatin-5R-lactone N-(4-(4-fluorophenyl)-5-((E)-2-((2S,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)vinyl)-6-isopropylpyriMidin-2-yl)-N-MethylMethanesulfonaMide Rosuvastatin lactone, >=98% Rosuvastatin EP Impurity D Rosuvastatin (5S)-Lactone/N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonam Rosuvastatin Impurity 1/Rosuvastatin EP Impurity D/Rosuvastatin (3R,5S)-Lactone Rosuvastatin calcium-5 Rosuvastatin EP Imp D Rosuvastatin Impurity 6(Rosuvastatin EP Impurity D) Rosuvastatin Lactone EP impurity D Rosuvastatin Calcium EP Impurity D 1-[4-[2-HYDROXY-3-[(1-METHYL-ETHYL)AMINO]PROPOXY]-1H-INDOL-1-YL]-3-[(1-METHYLETHYL)AMINO]PROPAN-2-OL Rsosuvastatin Lactone Rosuvastatin calcium impurity D Rosuvastatin (5S)-Lactone/N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide/N-[4-(4-Fluorophenyl)-5-{(E)-2-[(2S ,4R )-4-hydroxy-6-oxotetrahydro-2H -pyran-2- yl]vinyl}-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide Methanesulfonamide, N-[4-(4-fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methyl- Rosuvastatin EP Impurity D (Rosuvastatin (3R,5S)-Lactone) Rosuvastatin Impurity-D(lactone) Rosuvastatin LactoneQ: What is Rosuvastatin Lactone Q: What is the CAS Number of Rosuvastatin Lactone Q: What is the storage condition of Rosuvastatin Lactone Q: What are the applications of Rosuvastatin Lactone rahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide Rosuvastatin Lactone I (Rosuvastatin 5S Lactone) (EP Impurity D) 3-Benzofuranpropanenitrile,β-oxo- Benzenesulfonylchloride,4-methoxy-2-methyl-5-(2-methylethyl)- Rosuvastatin EP Impurity D (Calcium Salt) Rosuvastatin EP Impurity D N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)- tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2- pyrimidinyl]-N-methyl-methanesulfonamide N-[4-(4-Fluorophenyl)-5-[(E)-2-[(2S,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethenyl]-6-(1-methyl Rosuvastatin Impurity D 503610-43-3 Aromatics Chiral Reagents Intermediates & Fine Chemicals Isotopically Labeled Pharmaceutical Reference Standard Pharmaceuticals Sulfur & Selenium Compounds