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MK-8617

MK-8617 Structure
CAS No.
1187990-87-9
Chemical Name:
MK-8617
Synonyms
MK-8617;CS-2700;MK 8617;MK8617;N-[BIS(4-METHOXYPHENYL)METHYL]-6-OXO-2-PYRIDAZIN-3-YL-1H-PYRIMIDINE-5-CARBOXAMIDE;N-(bis(4-Methoxyphenyl)Methyl)-4-hydroxy-2-(pyridazin-3-yl)pyriMidine-5-carboxaMide;5-Pyrimidinecarboxamide,N-[bis(4-methoxyphenyl)methyl]-1,6-dihydro-6-oxo-2-(3-pyridazinyl)-;N-(bis(4-methoxyphenyl)methyl)-6-oxo-2-(pyridazin-3-yl)-1,6-dihydropyrimidine-5-carboxamide;MK-8617,MK 8617,HIF-PH,inhibit,Hypoxia-inducible factors,HIFs,Inhibitor,HIF/HIF Prolyl-Hydroxylase
CBNumber:
CB52516065
Molecular Formula:
C24H21N5O4
Molecular Weight:
443.45
MOL File:
1187990-87-9.mol
Modify Date:
2024/7/2 8:55:11
Request For Quotation

MK-8617 Properties

Density 1.32±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO:5.67(Max Conc. mg/mL);12.79(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:3):0.25(Max Conc. mg/mL);0.56(Max Conc. mM)
DMF:1.0(Max Conc. mg/mL);2.25(Max Conc. mM)
form A solid
pka 5.54±0.50(Predicted)
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P271-P280-P301+P312-P330-P302+P352-P321-P304+P340-P305+P351+P338-P332+P313-P362+P364-P337+P313-P403+P233-P405-P501
NFPA 704
0
2 0

MK-8617 Chemical Properties,Uses,Production

Uses

MK-8617 is a potent, selective and bioavailable hypoxia-inducible factor prolyl hydroxylase 1-3 (HIF PHD1-3) inhibitor used in the treatment of anemia.

MK-8617 Preparation Products And Raw materials

Raw materials

Preparation Products

MK-8617 Suppliers

Global( 55)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
LEAP CHEM CO., LTD. +86-852-30606658 China 24738 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
Henan Fengda Chemical Co., Ltd +86-371-86557731 +86-13613820652 China 20327 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry
Supplier Advantage
A.J Chemicals 58
ATK CHEMICAL COMPANY LIMITED 60
career henan chemical co 58
Zhejiang J&C Biological Technology Co.,Limited 58
InvivoChem 58
LEAP CHEM CO., LTD. 58
TargetMol Chemicals Inc. 58
Henan Fengda Chemical Co., Ltd 58
Aladdin Scientific 58
Amadis Chemical Company Limited 58

1187990-87-9(MK-8617)Related Search:

N-{4-[(2-Aminopyridin-4-yl)oxy]-3-fluorophenyl}-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide N-ACETYL-ALPHA-D-GLUCOSAMINE N-BOC-HEXAHYDRO-5-OXOCYCLOPENTA[C]PYRROLE N-BOC-6-azaspiro[3.4]octan-2-ol CP-456773 sodium
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N-Boc-endo-3-aminotropane N-(3-HYDROXYPROPYL)ETHYLENEDIAMINE
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N-(bis(4-methoxyphenyl)methyl)-6-oxo-2-(pyridazin-3-yl)-1,6-dihydropyrimidine-5-carboxamide 5-Pyrimidinecarboxamide,N-[bis(4-methoxyphenyl)methyl]-1,6-dihydro-6-oxo-2-(3-pyridazinyl)- MK-8617 N-(bis(4-Methoxyphenyl)Methyl)-4-hydroxy-2-(pyridazin-3-yl)pyriMidine-5-carboxaMide CS-2700 MK 8617;MK8617 N-[BIS(4-METHOXYPHENYL)METHYL]-6-OXO-2-PYRIDAZIN-3-YL-1H-PYRIMIDINE-5-CARBOXAMIDE MK-8617,MK 8617,HIF-PH,inhibit,Hypoxia-inducible factors,HIFs,Inhibitor,HIF/HIF Prolyl-Hydroxylase 1187990-87-9