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Hydroxy(2-naphthyl)Methanephosphonic Acid

Hydroxy(2-naphthyl)Methanephosphonic Acid Structure
CAS No.
132541-52-7
Chemical Name:
Hydroxy(2-naphthyl)Methanephosphonic Acid
Synonyms
Hydroxy(2-naphthyl)Methanephosphonic Acid;P-(Hydroxy-2-naphthalenylMethyl)phosphonic Acid;Phosphonic acid, P-(hydroxy-2-naphthalenylmethyl)-;Inhibitor,HNMPA,serine autophosphorylation,tyrosine autophosphorylation,tyrosine kinase,Insulin Receptor,inhibit
CBNumber:
CB52545214
Molecular Formula:
C11H11O4P
Molecular Weight:
238.18
MOL File:
132541-52-7.mol
Modify Date:
2023/9/4 15:50:00
Request For Quotation

Hydroxy(2-naphthyl)Methanephosphonic Acid Properties

Melting point >180oC(dec.)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility DMSO, Methanol
form White solid.
color White to Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362+P364-P403+P233-P501c

Hydroxy(2-naphthyl)Methanephosphonic Acid Chemical Properties,Uses,Production

Description

HNMPA is a cell impermeable tyrosine kinase inhibitor that blocks receptor serine and tyrosine phosphorylation, including insulin receptor tyrosine kinase activity. It does not affect protein kinase C or cyclic AMP-dependent protein kinase activities. HNMPA inhibits the insulin-stimulated autophosphorylation of the 95-kDa β-subunit of the insulin receptor with an IC50 value of 200 μM in vitro.

Uses

Insulin receptor tyrosine kinase (IRTK) inhibitor.

Hydroxy(2-naphthyl)Methanephosphonic Acid Preparation Products And Raw materials

Raw materials

(Hydroxy-2-naphthalenylmethyl)phosphonic Acid Bis(1,1-Dimethylethyl) Ester

Preparation Products

Hydroxy(2-naphthyl)Methanephosphonic Acid Suppliers

Global( 18)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 China 49739 58 Inquiry
TargetMol Chemicals Inc. 4008200310 China 23963 58 Inquiry
Cayman Chemical Company (800) 364-9897 United States 6618 81 Inquiry
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 China 9707 58 Inquiry
BOC Sciences USA 0 65 Inquiry
Toronto Research Chemicals +1 (416) 665-9696 Canada 6088 71 Inquiry
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 China 96815 76 Inquiry
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684 China 56070 58 Inquiry
ApexBio Technology + 1-832-696-8203 United States 6254 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 58
TargetMol Chemicals Inc. 58
Cayman Chemical Company 81
Shanghai EFE Biological Technology Co., Ltd. 58
BOC Sciences 65
Toronto Research Chemicals 71
J & K SCIENTIFIC LTD. 76
Shenzhen Polymeri Biochemical Technology Co., Ltd. 58
ApexBio Technology 58

Hydroxy(2-naphthyl)Methanephosphonic Acid Spectrum

Hydroxy(2-naphthyl)Methanephosphonic Acid(132541-52-7)1HNMR

132541-52-7(Hydroxy(2-naphthyl)Methanephosphonic Acid)Related Search:

(-)PPP HNMPA-(AM)3
Hydroxy(2-naphthyl)Methanephosphonic Acid P-(Hydroxy-2-naphthalenylMethyl)phosphonic Acid Phosphonic acid, P-(hydroxy-2-naphthalenylmethyl)- Inhibitor,HNMPA,serine autophosphorylation,tyrosine autophosphorylation,tyrosine kinase,Insulin Receptor,inhibit 132541-52-7 C11H11O4P Aromatics Intermediates & Fine Chemicals Pharmaceuticals Tyrosine Kinase Inhibitors Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals, Tyrosine Kinase Inhibitors