5(6)-Carboxyfluorescein
![5(6)-Carboxyfluorescein Structure](CAS/GIF/72088-94-9.gif)
- CAS No.
- 72088-94-9
- Chemical Name:
- 5(6)-Carboxyfluorescein
- Synonyms
- 5(6)-FAM;DCFA;5(6)-Carboxyfluoresc;5(6)-CARBOXYLUORESCEIN;4(5)-CARBOXYFLUORESCEIN;5(6)-CARBOXYFLUORESCEIN;5(6)-Carboxyfluoresceine];4(5)-Carboxyfluoresceine];Fluoresceincarboxylic Acid;5(6)-CARBOXYFLUORESCEIN 99%
- CBNumber:
- CB5257173
- Molecular Formula:
- C42H24O14
- Molecular Weight:
- 752.63
- MOL File:
- 72088-94-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/6/24 22:20:23
Melting point | 275 °C |
---|---|
Boiling point | 464.9°C (rough estimate) |
Density | 1.3418 (rough estimate) |
refractive index | 1.6380 (estimate) |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
solubility | DMSO (Sparingly), Methanol (Slightly, Heated) |
form | Solid |
color | Light Yellow to Dark Brown |
Water Solubility | slightly soluble |
InChIKey | CPRVUBZYHZGASQ-UHFFFAOYSA-N |
SMILES | C12(OC(=O)C3C=CC(C(=O)O)=CC1=3)C1=CC=C(O)C=C1OC1C=C(O)C=CC2=1.C12(OC(=O)C3C=C(C(=O)O)C=CC1=3)C1=CC=C(O)C=C1OC1C=C(O)C=CC2=1 |
EPA Substance Registry System | Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-ar-carboxylic acid, 3',6'-dihydroxy-3-oxo- (72088-94-9) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H319 | |||||||||
Precautionary statements | P305+P351+P338 | |||||||||
Hazard Codes | Xi,Xn | |||||||||
Risk Statements | 36-36/37/38-20/21/22 | |||||||||
Safety Statements | 37/39-26-36-22 | |||||||||
WGK Germany | 3 | |||||||||
TSCA | Yes | |||||||||
HS Code | 29322090 | |||||||||
NFPA 704 |
|
5(6)-Carboxyfluorescein price More Price(8)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 8.51082 | 5(6)-Carboxyfluorescein Novabiochem? | 72088-94-9 | 1G | ₹3080.01 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 8.51082 | 5(6)-Carboxyfluorescein Novabiochem? | 72088-94-9 | 5G | ₹12540 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 447293 | 5(6)-Carboxyfluorescein Dye content 90?% | 72088-94-9 | 1G | ₹7881 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 447293 | 5(6)-Carboxyfluorescein Dye content 90?% | 72088-94-9 | 5G | ₹25929.6 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 21877 | 5(6)-Carboxyfluorescein BioReagent, suitable for fluorescence, ≥95% (HPLC) | 72088-94-9 | 1G | ₹5283.6 | 2022-06-14 | Buy |
5(6)-Carboxyfluorescein Chemical Properties,Uses,Production
Description
5(6)-Carboxyfluorescein is a mixture of 5-carboxy and 6-carboxy derivatives of fluorescein. It is commonly used to label biomolecules through a reaction involving the carboxyl group. Unlike its succinimidyl ester derivative CFSE , 5(6)-carboxyfluorescein is membrane impermeant. As a result, it can be used in studies of membrane permeability. 5(6)-Carboxyfluorescein displays excellent fluorescence (excitation/emission at 492/514 nm, respectively), and its excitation maximum closely matches the 488 nm spectral line of argon-ion lasers.
Chemical Properties
Dark-Orange to Brown Solid
Uses
As a popular probe of determination of intracellular pH, 5(6)-Carboxyfluoresceincan be used as useful reagent for the preparation of hydrolytically stable fluorescent conjugates and a useful starting material for the synthesis of other fluorescein-derives reagent
Solubility in organics
5(6)-Carboxyfluorescein is soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide. The solubility of 5(6)-carboxyfluorescein in these solvents is approximately 5, 0.5, and 1 mg/ml, respectively.
5(6)-Carboxyfluorescein Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
Hongxiong | +undefined18915499068 | China | 120 | 58 | Inquiry |
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | China | 12447 | 58 | Inquiry |
Hebei Yanxi Chemical Co., Ltd. | +86-17531190177; +8617531190177 | China | 5873 | 58 | Inquiry |
Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 | China | 2989 | 58 | Inquiry |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | China | 20294 | 58 | Inquiry |
hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 | China | 973 | 58 | Inquiry |