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GW 627368X

GW 627368X Structure
CAS No.
439288-66-1
Chemical Name:
GW 627368X
Synonyms
CS-1654;GW 627368;GW 627368X;GW627368(GW627368X);GW 627368;GW-627368;GW627368;GW-627368X;GW627368X;GW 627368X;inhibit,Inhibitor,Prostaglandin Receptor,GW627368,GW 627368,GW-627368;N-(benzenesulfonyl)-2-[4-(4,9-diethoxy-3-oxo-1H-benzo[f]isoindol-2-yl)phenyl]acetamide;2-(4-(4,9-Diethoxy-1-oxo-1H-benzo[f]isoindol-2(3H)-yl)phenyl)-N-(phenylsulfonyl)acetamide;4-(4,9-Diethoxy-1,3-dihydro-1-oxo-2H-benz[f]isoindol-2-yl)-N-(phenylsulfonyl)benzeneacetamide;Benzeneacetamide, 4-(4,9-diethoxy-1,3-dihydro-1-oxo-2H-benz[f]isoindol-2-yl)-N-(phenylsulfonyl)-
CBNumber:
CB52591190
Molecular Formula:
C30H28N2O6S
Molecular Weight:
544.62
MOL File:
439288-66-1.mol
Modify Date:
2024/7/2 8:55:11
Request For Quotation

GW 627368X Properties

Density 1.327±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Store in freezer, under -20°C
solubility DMSO : 100 mg/mL (183.61 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form Powder
pka 5.25±0.10(Predicted)
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
NFPA 704
0
2 0

GW 627368X Chemical Properties,Uses,Production

Description

The effects of prostaglandin E2 (PGE2) are transduced by at least four distinct receptors designated EP1, EP2, EP3, and EP4. GW 627368X is a potent and selective competitive antagonist of the EP4 receptor with additional human TP receptor affinity. In competition radioligand bioassays, GW 627368X had affinity for human EP4 and TP receptors with Ki values of 100 nM and 158 nM, respectively. Affinity for all other human prostanoid receptors is >5.0 μM. In human washed platelets, GW 627368X produced 100% inhibition of U-46619 (EC100)-induced aggregation at a concentration of 10 μM.

Uses

GW 627368 is a selective EP4 receptor competitive antagonist.

GW 627368X Preparation Products And Raw materials

Raw materials

Preparation Products

GW 627368X Suppliers

Global( 65)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
Alfa Chemistry +1-5166625404 United States 21317 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
Nantong HI-FUTURE Biology Co., Ltd. +undefined18051384581 China 3136 58 Inquiry
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 China 11681 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 60
BOC Sciences 58
career henan chemical co 58
TargetMol Chemicals Inc. 58
Zhejiang J&C Biological Technology Co.,Limited 58
Alfa Chemistry 58
InvivoChem 58
Nantong HI-FUTURE Biology Co., Ltd. 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 58
Aladdin Scientific 58

GW 627368X Spectrum

GW 627368X(439288-66-1)1HNMR

439288-66-1(GW 627368X)Related Search:

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GW806742X ONO-AE3-208 CJ 033466 CJ-21058 CJ-42794
L-161,982 Grapiprant
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GW 627368X GW 627368 4-(4,9-Diethoxy-1,3-dihydro-1-oxo-2H-benz[f]isoindol-2-yl)-N-(phenylsulfonyl)benzeneacetamide 2-[4-(4,9-Diethoxy-1-oxo-1,3-dihydro-2H-benzo[f]isoindol-2-yl)phenyl]-N-(phenylsulfonyl)acetamide GW 627368;GW-627368;GW627368;GW-627368X;GW627368X;GW 627368X CS-1654 GW627368(GW627368X) N-(benzenesulfonyl)-2-[4-(4,9-diethoxy-3-oxo-1H-benzo[f]isoindol-2-yl)phenyl]acetamide 2-(4-(4,9-Diethoxy-1-oxo-1H-benzo[f]isoindol-2(3H)-yl)phenyl)-N-(phenylsulfonyl)acetamide Benzeneacetamide, 4-(4,9-diethoxy-1,3-dihydro-1-oxo-2H-benz[f]isoindol-2-yl)-N-(phenylsulfonyl)- inhibit,Inhibitor,Prostaglandin Receptor,GW627368,GW 627368,GW-627368 439288-66-1 Inhibitors