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ChemicalBook > Product Catalog >Pharmaceutical intermediates >Bulk Drug Intermediates >4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline

4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline

4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline Structure
CAS No.
190728-25-7
Chemical Name:
4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline
Synonyms
Benzenam;4-(6,7-Dimethoxy-quinoL;Cabozantinib Amine Analog;Intermediate 1 of Cabozantinib;Cabozantinib Genotoxic Impurity I;4-[(6,7-dimethoxy-4-quinolinyl)oxy]-;4-(6,7-dimethoxy quinolinoxy) aniline;4-[(6,7-Dimethoxy-4-quinolyl)oxy]aniline;6,7-Dimethoxy-4-(4-aminophenoxy)quinoline;4-(4-Aminophenoxy)-6,7-dimethoxyquinoline
CBNumber:
CB52652846
Molecular Formula:
C17H16N2O3
Molecular Weight:
296.32
MOL File:
190728-25-7.mol
MSDS File:
SDS
Modify Date:
2023/12/26 17:07:23
Request For Quotation

4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline Properties

Melting point 211.0 to 215.0 °C
Boiling point 481.8±45.0 °C(Predicted)
Density 1.246±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO (Slightly, Sonicated), Methanol (Slightly)
form powder to crystal
pka 6.79±0.30(Predicted)
color Light yellow to Brown
InChI InChI=1S/C17H16N2O3/c1-20-16-9-13-14(10-17(16)21-2)19-8-7-15(13)22-12-5-3-11(18)4-6-12/h3-10H,18H2,1-2H3
InChIKey VXEQRXJATQUJSN-UHFFFAOYSA-N
SMILES C1(N)=CC=C(OC2C3C(N=CC=2)=CC(OC)=C(OC)C=3)C=C1

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
HS Code  2933.49.7000
NFPA 704
0
2 0

4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemicals (India) D5070 4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline 190728-25-7 200MG ₹9600 2022-05-26 Buy
TCI Chemicals (India) D5070 4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline 190728-25-7 1G ₹38100 2022-05-26 Buy
Product number Packaging Price Buy
D5070 200MG ₹9600 Buy
D5070 1G ₹38100 Buy

4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline Chemical Properties,Uses,Production

Uses

4-(6,7-Dimethoxy-Quinolin-4-Yloxy)-Phenylamine is used in preparation of Cabozantinib Defluorination impurity.

Chemical Reactivity

4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline is a primary alcohol that has been shown to catalyze the reaction of potassium carbonate with an alkali metal hydroxide to produce potassium. It has also been shown to be a base catalyst for the reaction of cyclopropanecarboxylic acid with an alcohol ester to produce high yield.

4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline Preparation Products And Raw materials

Raw materials

Preparation Products

Cabozantinib

4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline Suppliers

Global( 199)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Credas Labs Pvt Ltd +91 9133918031 Hyderabad, India 119 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Archerchem Healthcare Pvt., Ltd. (part of Archerchem Group) 91-22-42361111 Maharashtra, India 147 58 Inquiry
Clearsynth Labs 91-22-45045900 Maharashtra, India 3889 58 Inquiry
ALTAIR ALCHEMY Laboratories 91--9014276848 Hyderabad, India 324 58 Inquiry
Huanfu Industrial Co.，（Shanghai）Ltd. +86-18001856580 +86-18001856580 China 43 58 Inquiry
Supplier Advantage
Credas Labs Pvt Ltd 58
Pharma Affiliates 58
TCI Chemicals (India) Pvt. Ltd. 58
CLEARSYNTH LABS LTD. 58
A.J Chemicals 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
Archerchem Healthcare Pvt., Ltd. (part of Archerchem Group) 58
Clearsynth Labs 58
ALTAIR ALCHEMY Laboratories 58
Huanfu Industrial Co.，（Shanghai）Ltd. 58

190728-25-7(4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline)Related Search:

1-(4-Fluorophenylcarbamoyl)cyclopropanecarboxylic acid Cabozantinib Malate
BenzenaMine, 4-[(6,7-diMethoxy-4-quinolinyl)oxy]- [4-[(6,7-Dimethoxyquinolin-4-yl)oxy]phenyl]amine 4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline 6,7-Dimethoxy-4-(4-aminophenoxy)quinoline BenzeMine, 4-[(6,7-diMethoxy-4-quinolinyl)oxy]- 4-[(6,7-diMethoxy-4-quinolinyl)oxy]-BenzenaMine 4-(2,3-dimethoxynaphthalen-5-yloxy)benzenamine Intermediate 1 of Cabozantinib 4-(6,7-dimethoxy quinolinoxy) aniline 4-[(6,7-dimethoxy-4-quinolinyl)oxy]- 6,7-Dimethoxy-4-(4-aminophenyloxy)quinolone 4-[(6,7-dimethoxyquinolin-4-yl)oxy]aniline 4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline Cabozantinib Genotoxic Impurity I 4-(6,7-Dimethoxy-quinoL 4-(4-Aminophenoxy)-6,7-dimethoxyquinoline CAS 190728-25-7 BenzenaMine, 4-[(6,7-diMethoxy-4-quinolinyl)oxy]- 4-[(6,7-Dimethoxy-4-quinolyl)oxy]aniline Cabozantinib Amine Analog Benzenam 1-((6,7-dimethoxyquinolin-4-yl)oxy)aniline 4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline? (Cabozantinib Impurity) 4-(6,7-dimethoxy quinoline-4-yloxy)phenylamine 190728-25-7 190827-25-7