Cinacalcet IMpurity 5

Cinacalcet IMpurity 5 Structure
CAS No.
1431699-53-4
Chemical Name:
Cinacalcet IMpurity 5
Synonyms
Cinacalcet Impurity 87;Cinacalcet Hydrochloride iMpuritF;3'-Destrifluoromethyl 2'-Trifluoromethyl Cinacalcet;(E)-N-(1-(7,8-dihydrophthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)acrylamide;1-Naphthalenemethanamine, α-methyl-N-[3-[2-(trifluoromethyl)phenyl]propyl]-, (αR)-;Cinacalcet ortho isomer-(3-(2-(trifluoromethyl)phenyl)-N-((R)-1-(naphthalen-5-yl)ethyl)propan-1-amine)
CBNumber:
CB52673834
Molecular Formula:
C22H22F3N
Molecular Weight:
357.42
MOL File:
1431699-53-4.mol
Modify Date:
2023/4/23 13:52:06

Cinacalcet IMpurity 5 Properties

Boiling point 439.7±45.0 °C(Predicted)
Density 1.154±0.06 g/cm3(Predicted)
solubility Dichloromethane, Ethyl Acetate, Methanol
form Oil
pka 9.15±0.29(Predicted)
color Pale

Cinacalcet IMpurity 5 Chemical Properties,Uses,Production

Uses

3''-Destrifluoromethyl 2''-Trifluoromethyl Cinacalcet is an intermediate in synthesizing 3''-Destrifluoromethyl 2''-Trifluoromethyl Cinacalcet Hydrochloride (D297820), a related compound of Cinacalcet Hydrochloride (C441800), which is the (R) enantiomer of Cinacalcet. Used in clinical trial in secondary hyperparathyroidism.

Cinacalcet IMpurity 5 Preparation Products And Raw materials

Raw materials

Preparation Products

Cinacalcet Hydrochloride iMpuritF 3'-Destrifluoromethyl 2'-Trifluoromethyl Cinacalcet (E)-N-(1-(7,8-dihydrophthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)acrylamide Cinacalcet Impurity 87 1-Naphthalenemethanamine, α-methyl-N-[3-[2-(trifluoromethyl)phenyl]propyl]-, (αR)- Cinacalcet ortho isomer-(3-(2-(trifluoromethyl)phenyl)-N-((R)-1-(naphthalen-5-yl)ethyl)propan-1-amine) 1431699-53-4