ChemicalBook > Product Catalog >Pharmaceutical intermediates >Heterocyclic compound >Pyridine compound >Bromopyridine >Ethyl 6-bromopicolinate
Ethyl 6-bromopicolinate
- CAS No.
- 21190-88-5
- Chemical Name:
- Ethyl 6-bromopicolinate
- Synonyms
- RARECHEM AL BI 0899;ETHYL 6-BROMOPICOLINATE;Ethyl 6-bromo-2-picolinate;2,5-Difluoro-5-iodopyridine;6-Bromopicolinic acid ethyl ester;2-Bromo-6-(ethoxycarbonyl)pyridine;ETHYL-6-BROMO-2-PYRIDINECARBOXYLATE;ETHYL 6-BROMOPYRIDINE-2-CARBOXYLATE;6-BROMOPYRIDINE-2-ETHYL CARBOXYLATE;METHYL 2-BROMOPYRIDINE-6-CARBOXYLATE
- CBNumber:
- CB5271364
- Molecular Formula:
- C8H8BrNO2
- Molecular Weight:
- 230.06
- MOL File:
- 21190-88-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/4/8 13:48:25
| Melting point | 41-42°C |
|---|---|
| Boiling point | 302.7±22.0 °C(Predicted) |
| Density | 1.501±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| pka | -0.89±0.10(Predicted) |
| form | solid |
| color | Off-white |
| CAS DataBase Reference | 21190-88-5(CAS DataBase Reference) |
Ethyl 6-bromopicolinate Chemical Properties,Uses,Production
Uses
ethyl 6-bromopicolinate is a model compound for the preliminary screening of dimerization reaction.
Preparation
Ethyl 6-bromopicolinate was prepared by monolithiation of 2,6-dibromopyridine followed by a reaction with ethyl formate and subsequently by a reaction with iodine in ethanol (Scheme 57). This three-step procedure furnished the required ethyl 6-bromopicolinate in 45% yield.
Synthesis of Ethyl 6-bromopicolinate
Ethyl 6-bromopicolinate Preparation Products And Raw materials
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| TCI Chemicals (India) Pvt. Ltd. | 58 |
| VASIN BIO LIFE SCIENCES PVT LTD | 58 |
| A.J Chemicals | 58 |
| Sakam Finechem Pvt., Ltd. | 58 |
| Novasyn Organics Pvt. Ltd (India) | 58 |
| Dr Chindepalli | 58 |
| Reax Chemicals | 58 |
| Siri Life Sciences | 58 |
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21190-88-5
blocks
Bromides
Pyridines
Pyridine
Pyridine Series
Heterocycle-Pyridine series