Pyrazofurin

Pyrazofurin Structure
CAS No.
30868-30-5
Chemical Name:
Pyrazofurin
Synonyms
PRZF;47599;A-23813;nsc143095;pyrazofurin;pirazofurin;Pyrazomycin;Pyrozofurin;compound47599;β-Pyrazofurin
CBNumber:
CB5276253
Molecular Formula:
C9H13N3O6
Molecular Weight:
259.22
MOL File:
30868-30-5.mol
MSDS File:
SDS
Modify Date:
2024/7/22 17:51:23

Pyrazofurin Properties

Boiling point 584.4±50.0 °C(Predicted)
Density 1.785±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility DMSO, Water (Slightly)
pka 7.17±0.50(Predicted)
form powder
color white to light brown
optical activity [α]/D -49 to -39°, c = 0.5 in H2O
Stability Hygroscopic

Pyrazofurin price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) SML1502 Pyrazofurin ≥98% (HPLC) 30868-30-5 5MG ₹14873.55 2022-06-14 Buy
Sigma-Aldrich(India) SML1502 Pyrazofurin ≥98% (HPLC) 30868-30-5 25MG ₹59862.25 2022-06-14 Buy
Product number Packaging Price Buy
SML1502 5MG ₹14873.55 Buy
SML1502 25MG ₹59862.25 Buy

Pyrazofurin Chemical Properties,Uses,Production

Uses

Geldanamycin (G304500) derivative.

Definition

ChEBI: A C-glycosyl compound that is 4-hydroxy-1H-pyrazole-5-carboxamide in which the hydrogen at position 3 has been replaced by a beta-D-ribofuranosyl group.

Enzyme inhibitor

This pyrimidine nucleoside (FW = 261.23 g/mol), also known as pyrazomycin, exhibits antineoplastic activity and inhibits cell proliferation and DNA synthesis in cells by inhibiting orotidylate decarboxylase (uridine 5'-phosphate synthase). Pyrazofurin, also known as 3,b-D-ribofuranosyl-4- hydroxypyrazole-5-carboxamide, is the prodrug of the 5’-phosphate derivative. Target(s): adenosylhomocysteinase; 5-aminoimidazole-4- carboxamide-1-b-D-ribofuranosyl 5'-monophosphate formyltransferase; orotate phosphoribosyltransferase; orotidylate decarboxylase, or UMP synthase.

Pyrazofurin Preparation Products And Raw materials

Raw materials

Preparation Products

Pyrazofurin Suppliers

Global( 30)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Shaanxi Dideu Medichem Co. Ltd +86-029-81138252 +86-18789408387 China 3632 58 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Alfa Chemistry United States 24072 58 Inquiry
Shanghai Tachizaki Biomedical Research Center 18014399201 China 2539 58 Inquiry
Baoji Didu Pharmaceutical and Chemical Co., Ltd 029-61856358 15829046862 China 10011 58 Inquiry
Shanghai Maclean Biochemical Technology Co., LTD 021-50706066 15221275939 China 29803 58 Inquiry
RD International Technology Co., Limited 18024082417 China 9274 58 Inquiry
Meryer (Shanghai) Chemical Technology Co., Ltd. 18621169085 China 27996 58 Inquiry
3-beta-d-ribofuranosyl-4-hydroxypyrazole-5-carboxamide 4-hydroxy-3-beta-d-ribofuranosyl-1h-pyrazole-5-carboxamid 4-hydroxy-3-beta-d-ribofuranosyl-1h-pyrazole-5-carboxamide antibiotica23813 beta-pyrazomycin compound47599 nsc143095 pirazofurin pyrazofurin PYRAZOFURIN MONOHYDRATE 4-HYDROXY-3-BETA-D-RIBOFURANOSYL-1H-PYRAZOLE-5-CARBOXAMIDE MONOHYDRATE 47599 A-23813 1H-Pyrazole-5-carboxamide, 4-hydroxy-3-beta-D-ribofuranosyl- 4-Hydroxy-3-beta-D-ribofuranosylpyrazole-5-carboxamide PRZF Pyrazole-3-carboxamide, 4-hydroxy-5-beta-L-ribofuranosyl- Pyrazomycin Pyrozofurin 1H-Pyrazole-5-carboxamide, 4-hydroxy-3-β-D-ribofuranosyl- β-Pyrazofurin --Pyrazofurin Pyrazomycin Ⅰ 30868-30-5 Bases & Related Reagents Intermediates & Fine Chemicals Nucleotides Pharmaceuticals