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PD 158780

PD 158780 Structure
CAS No.
Chemical Name:
PD 158780
Synonyms
PD 158780;4-[(3-BROMOPHENYL)AMINO]-6-(METHYLAMINO)-PYRIDO[3,4-D]PYRIDIMINE
CBNumber:
CB5326060
Molecular Formula:
C14H12BrN5
Molecular Weight:
330.18
MOL File:
Mol file
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PD 158780 Properties

storage temp. -20°C

PD 158780 Chemical Properties,Uses,Production

Enzyme inhibitor

This photosensitive pyridopyrimidine (FW = 330.19 g/mol), known systematically as 4-[(3-bromophenyl)amino]-6-(methylamino)pyrido[3,4- d]pyridimine, inhibits EPGFR (epidermal growth factor receptor) proteintyrosine kinase (IC50 = 8 pM). In addition, PD 158780 inhibits heregulinstimulated autophosphorylation in SK-BR-3 (IC50 = 49 nM) and MDA-MB- 453 (IC50 = 52 nM) breast carcinomas.

PD 158780 Preparation Products And Raw materials

Raw materials

Preparation Products

PD 158780 Suppliers

Global( 37)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Nacalai Tesque, Inc. 81 75 251 1723 Japan 6048 75 Inquiry
Kanto Chemical Co., Inc. +81 3 3663 7631 Japan 6762 74 Inquiry
EMD Biosciences, Inc. 858 450 5500 United States 6529 66 Inquiry
VWR International 800 932 5000 United Kingdom 6554 82 Inquiry
Beijing Fubo Biotechnology Co., Ltd. 010-57263844 13260236521 CHINA 6039 58 Inquiry
Shanghai Yaoyun Biological Technology Co., Ltd. 400-002-6926 400-002-6926 CHINA 6852 58 Inquiry
Qingdao Jieshikang Biotechnology Co., Ltd. 4009025885 18754289606 CHINA 4012 58 Inquiry
Beijing Xiangsheng Xingye Technology Co., Ltd. 0136-81184382 13681184382 CHINA 5130 58 Inquiry
Shanghai Benrui Biotechnology Co., Ltd. 13917534498 CHINA 1472 58 Inquiry
Shanghai Weiwei Biological Technology Co., Ltd. 021-55669583 18616258598 CHINA 4398 58 Inquiry
Supplier Advantage
Nacalai Tesque, Inc. 75
Kanto Chemical Co., Inc. 74
EMD Biosciences, Inc. 66
VWR International 82
Beijing Fubo Biotechnology Co., Ltd. 58
Shanghai Yaoyun Biological Technology Co., Ltd. 58
Qingdao Jieshikang Biotechnology Co., Ltd. 58
Beijing Xiangsheng Xingye Technology Co., Ltd. 58
Shanghai Benrui Biotechnology Co., Ltd. 58
Shanghai Weiwei Biological Technology Co., Ltd. 58

(PD 158780)Related Search:

PD168393 4-(4-FLUOROPHENYL)-2-(4-NITROPHENYL)-5-(4-PYRIDYL)-1H-IMIDAZOLE PD153035 HCl N-[2-[[4-(DIETHYLAMINO)BUTYL]AMINO-6-(3,5-DIMETHOXYPHENYL)PYRIDO[2,3-D]PYRIMIDIN-7-YL]-N'-(1,1-DIMETHYLETHYL)UREA PD 166866
4-[(3-BROMOPHENYL)AMINO]-6-(METHYLAMINO)-PYRIDO[3,4-D]PYRIDIMINE PD 158780