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Antihistamine-1

Antihistamine-1 Structure
CAS No.
1186430-60-3
Chemical Name:
Antihistamine-1
Synonyms
Antihistamine-1;Antihistamine1,Antihistamine 1;1-[(4-Fluorophenyl)methyl]-2-[4-(4-methyl-1H-pyrazol-1-yl)-1-piperidinyl]-1H-benzimidazole;1H-Benzimidazole, 1-[(4-fluorophenyl)methyl]-2-[4-(4-methyl-1H-pyrazol-1-yl)-1-piperidinyl]-
CBNumber:
CB53384766
Molecular Formula:
C23H24FN5
Molecular Weight:
389.47
MOL File:
1186430-60-3.mol
Modify Date:
2024/7/2 8:55:11
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Antihistamine-1 Properties

Boiling point 596.0±60.0 °C(Predicted)
Density 1.28±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
form Solid
pka 7.66±0.10(Predicted)
color Off-white to light yellow

Antihistamine-1 Chemical Properties,Uses,Production

Uses

1-[(4-Fluorophenyl)methyl]-2-[4-(4-methyl-1H-pyrazol-1-yl)-1-piperidinyl]-1H-benzimidazole, is a 2-aminobenzimidazole H1-antihistamines used for the treatment of insomnia. It is also an inhibitor of CYP2D6 and hERG channel with IC50s of 5.4 and 0.8 μM.

Antihistamine-1 Preparation Products And Raw materials

Raw materials

1-(1-(4-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)piperidin-4-yl methanesulfonate(WXG02521) 4-Methylpyrazole

Preparation Products

Antihistamine-1 Suppliers

Global( 8)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
Angel Pharmatech, Ltd. 17317130613 China 3246 58 Inquiry
MedChemExpress 021-58955995 United States 6398 58 Inquiry
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 China 29778 58 Inquiry
TargetMol Chemicals Inc. 4008200310 China 24017 58 Inquiry
Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 15850508050 China 12007 58 Inquiry
Supplier Advantage
TargetMol Chemicals Inc. 58
Aladdin Scientific 58
Angel Pharmatech, Ltd. 58
MedChemExpress 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
TargetMol Chemicals Inc. 58
Nanjing Shizhou Biology Technology Co.,Ltd 58
1-[(4-Fluorophenyl)methyl]-2-[4-(4-methyl-1H-pyrazol-1-yl)-1-piperidinyl]-1H-benzimidazole Antihistamine-1 1H-Benzimidazole, 1-[(4-fluorophenyl)methyl]-2-[4-(4-methyl-1H-pyrazol-1-yl)-1-piperidinyl]- Antihistamine1,Antihistamine 1 1186430-60-3 C23H24FN5