Lefamulin acetate
- CAS No.
- 1350636-82-6
- Chemical Name:
- Lefamulin acetate
- Synonyms
- Lefamulin acetate;BC-3781 ACETATE;Lefamulin Acetat;BC-3781;BC 3781;BC3781;WSMXIQXWHPSVDE-WHAUHWDVSA-N;Lefamulin acetate (Xenleta);Lefamulin acetate (BC-3781 acetate);WSMXIQXWHPSVDE-WHAUHWDVSA-N USP/EP/BP;Inhibitor,Lefamulin,BC 3781,BC3781,Lefamulin acetate,inhibit,BC-3781,Bacterial,Antibiotic
- CBNumber:
- CB53399603
- Molecular Formula:
- C30H49NO7S
- Molecular Weight:
- 567.78
- MOL File:
- 1350636-82-6.mol
- Modify Date:
- 2024/7/2 8:55:11
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS07,GHS05,GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H315-H318-H317-H302-H330 |
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P280-P305+P351+P338-P310-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P264-P270-P301+P312-P330-P501-P260-P271-P284-P304+P340-P310-P320-P403+P233-P405-P501 |
Lefamulin acetate Chemical Properties,Uses,Production
Chemical Properties
Lefamulin acetate is a white to off-white solid. It is a stable compound (requiring no special storage conditions) which is highly soluble in water and 0.9% sodium chloride solution (>300mg/ml). The hydration level of lefamulin acetate at ambient conditions is typically below 1% w/w.
Uses
Lefamulin (BC-3781) acetate is an orally active antibiotic. Lefamulin acetate inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome. Lefamulin acetate has anti-inflammatory activity. Lefamulin acetate can be used in the research of bacterial infections, such as bacterial pneumonia.
Definition
Lefamulin acetate is a single stereoisomer semi-synthetically derived from pleuromutilin, a homochiral, natural fermentation product of known absolute stereochemistry. Lefamulin acetate is a diastereomer with R-configuration at carbons of the cyclohexane moiety. The absolute configuration of the active substance has been confirmed by single-crystal structure determination.
Lefamulin acetate Preparation Products And Raw materials
Raw materials
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Lefamulin acetate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Beijing Mesochem Technology Co.,Ltd | +8613651027935 | China | 191 | 58 | Inquiry |
| Changzhou Guiding Bio-Tech. Co.,Ltd. | +86-519-519-86686860 +8618795626222 | China | 299 | 58 | Inquiry |
| shandong perfect biotechnology co.ltd | +86-53169958659; +8618596095638 | China | 294 | 58 | Inquiry |
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | China | 1000 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
| Shanghai Rochi Pharmaceutical Co.,Ltd. | 21-38751876 +8615000076078 | China | 431 | 58 | Inquiry |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 26216 | 58 | Inquiry |