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TSH

TSH Structure
CAS No.
9002-71-5
Chemical Name:
TSH
Synonyms
BTSH;THYROTROPIN;THYROID STIMULATING HORMONE;Thyrotropin Alfa;TSH;HTSH;pretiron;thytropar;TSH HUMAN;TSH BOVINE
CBNumber:
CB5351862
Molecular Formula:
Molecular Weight:
0
MOL File:
Mol file
Modify Date:
2024/7/2 8:55:11

TSH Properties

storage temp. 2-8°C
form lyophilized powder
color White to off-white
Merck 13,9870

SAFETY

Risk and Safety Statements

Hazard Codes  B
WGK Germany  3
RTECS  XP3581600
10-21

TSH price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) T9265 Thyrotropic hormone from human pituitary lyophilized powder, ≥6.2?IU/mg (immunoassay) 9002-71-5 5μG ₹17049.38 2022-06-14 Buy
Sigma-Aldrich(India) T9265 Thyrotropic hormone from human pituitary lyophilized powder, ≥6.2?IU/mg (immunoassay) 9002-71-5 10μG ₹28361.5 2022-06-14 Buy
Sigma-Aldrich(India) T9265 Thyrotropic hormone from human pituitary lyophilized powder, ≥6.2?IU/mg (immunoassay) 9002-71-5 25μG ₹55618.85 2022-06-14 Buy
Sigma-Aldrich(India) T9265 Thyrotropic hormone from human pituitary lyophilized powder, ≥6.2?IU/mg (immunoassay) 9002-71-5 0.1MG ₹181329.58 2022-06-14 Buy
Sigma-Aldrich(India) T8931 Thyrotropic hormone from bovine pituitary 9002-71-5 1VIAL ₹20415.95 2022-06-14 Buy
Product number Packaging Price Buy
T9265 5μG ₹17049.38 Buy
T9265 10μG ₹28361.5 Buy
T9265 25μG ₹55618.85 Buy
T9265 0.1MG ₹181329.58 Buy
T8931 1VIAL ₹20415.95 Buy

TSH Chemical Properties,Uses,Production

Uses

Thyrogen (Genzyme).

Indications

TSH, or thyrotropin, is a glycosylated protein of two subunits,  and . TSH stimulates the thyroid gland to produce thyroid hormones. Deficiencies are treated by giving thyroxine itself rather than TSH, but TSH is available for diagnostic purposes to differentiate between pituitary and thyroid gland failure as causes of hypothyroidism.

Definition

A hormone secreted by the anterior lobe of the pituitary gland. It increases the rate of removal of iodine from the blood by the thyroid gland, synthesis of the thyroid hormone, and its release into the bloodstream. The thyrotropic hormone is a protein with a low molecular weight (about 10,000) that contains some carbohydrate.

General Description

The thyrotropic hormone, also called thyrotropin and thyroidstimulatinghormone (TSH), is a glycoprotein consisting oftwo polypeptide chains. This hormone promotes productionof thyroid hormones by affecting the kinetics of the mechanismby which the thyroid concentrates iodide ions from thebloodstream, thereby promoting incorporation of the halogeninto the thyroid hormones and release of hormones by thethyroid.
TSH (Thyropar) appears to be a glycoprotein (relativemolecular mass [Mr] 26,000–30,000) containing glucosamine,galactosamine, mannose, and fucose, whose homogeneityis yet to be established. It is produced by thebasophil cells of the anterior lobe of the pituitary gland.TSH enters the circulation from the pituitary, presumablytraversing cell membranes in the process. After exogenousadministration, it is widely distributed and disappears veryrapidly from circulation. Some evidence suggests that thethyroid may directly inactivate some of the TSH by an oxidationmechanism that may involve iodine. TSH thus inactivatedcan be reactivated by certain reducing agents.TSH regulates the production by the thyroid gland of thyroxine,which stimulates the metabolic rate. Thyroxinefeedback mechanisms regulate the production of TSH bythe pituitary gland.

Clinical Use

Recombinant form of human thyroidstimulating hormone (rhTSH). Used diagnostically for serum thyroglobulin testing.

TSH Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 46)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21669 55 Inquiry
Shaanxi Dideu Medichem Co. Ltd +86-029-89586680 +86-18192503167 China 9030 58 Inquiry
BOC Sciences 16314854226; +16314854226 United States 19743 58 Inquiry
Xiamen Eagle Chemical Limited Corporation +86-5925023701 +86-18900207489 China 6046 58 Inquiry
Watson Biotechnology Co.,Ltd +86-18186686046 +86-18186686046 China 5821 58 Inquiry
PhyCell Medical research Ltd 13818883417 China 25 58 Inquiry
Mitsubishi Chemical Europe GmbH 49-211-5205410 Germany 1252 58 Inquiry
OEM Concepts 877 341 3570 (Toll free) United States 540 50 Inquiry
Shanghai Sanhao Biological Technology Co., Ltd. 021-67891653 18202139324 CHINA 6411 58 Inquiry
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd 17691182729 18161915376 China 10011 58 Inquiry

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