N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE

CAS No.: 149649-22-9

Chemical Name:: N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE

Synonyms: NAFADOTRIDE;N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE;2-Naphthalenecarboxamide, N-[(1-butyl-2-pyrrolidinyl)methyl]-4-cyano-1-methoxy-

CBNumber:: CB5402878

Molecular Formula:: C22H27N3O2

Molecular Weight:: 365.47

MOL File:: 149649-22-9.mol

Request For Quotation

N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE Properties

Boiling point	556.6±40.0 °C(Predicted)
Density	1.17±0.1 g/cm3(Predicted)
storage temp.	Desiccate at RT
pka	12.84±0.46(Predicted)

N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE Chemical Properties,Uses,Production

Uses

Nafadotride is a highly potent and competitive dopamine D3 receptor (D3R) antagonist.

Definition

ChEBI: A naphthalenecarboxamide resulting from the formal condensation of the carboxylic acid group of 4-cyano-1-methoxynaphthalene-2-carboxylic acid with the primary amino group of 1-(1-butylpyrrolidin-2-yl]methanamine. It is a highly potent, competitive, prefer ntial dopamine D3 receptor antagonist, centrally active upon systemic administration.

Biological Activity

Highly potent, competitive, preferential dopamine D 3 receptor antagonist. K i values are 0.52, 5, and 269 nM for human cloned D 3 , D 2 and D 4 receptors respectively. Centrally active upon systemic administration.

N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE Suppliers

Global( 31)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CHEMSWORTH	+91-261-2397244	New Delhi, India	6707	30	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	52927	58	Inquiry
TargetMol Chemicals Inc.	15002134094	China	28091	58	Inquiry
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	China	8141	58	Inquiry
Wako Pure Chemical Industries, Ltd.	+81 6 6203 3741	Japan	6828	80	Inquiry
QUALITY CONTROL SOLUTIONS LTD.	13670046396	China	18865	58	Inquiry
Nanjing Tengyi Biotechnology Co., Ltd	025-58851786 17714337195	China	5587	58	Inquiry
Service Chemical Inc.	888-895-6920	Germany	6373	71	Inquiry
3B Scientific Corporation	847.281.9822	United States	6744	47	Inquiry
CARBONE SCIENTIFIC CO.,LTD	+44(0)870 486 8629	United Kingdom	6682	30	Inquiry

Supplier	Advantage
CHEMSWORTH	30
Aladdin Scientific	58
TargetMol Chemicals Inc.	58
MedBioPharmaceutical Technology Inc	58
Wako Pure Chemical Industries, Ltd.	80
QUALITY CONTROL SOLUTIONS LTD.	58
Nanjing Tengyi Biotechnology Co., Ltd	58
Service Chemical Inc.	71
3B Scientific Corporation	47
CARBONE SCIENTIFIC CO.,LTD	30

149649-22-9(N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE)Related Search:

3-CYANOBENZYLAMINE 3-Cyanobenzaldehyde 3-(methylaminomethyl)benzonitrile 3-CYANO-BENZAMIDE 3-Formyl-4-hydroxybenzonitrile

N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE 1-Cyanonaphthalene (-)-N[(N-BUTYL-2-PYRROLIDINYL)METHYL]-1-METHOXY-4-CYANONAPHTHALENE-2-CARBOXAMIDE TARTRATE 4-METHOXY-1-NAPHTHONITRILE

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NAFADOTRIDE N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE 2-Naphthalenecarboxamide, N-[(1-butyl-2-pyrrolidinyl)methyl]-4-cyano-1-methoxy- 149649-22-9 C22H27N3O2