N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE

CAS No.: 149649-22-9

Chemical Name:: N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE

Synonyms: NAFADOTRIDE;Nafadotride, D3 antagonist;N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE;2-Naphthalenecarboxamide, N-[(1-butyl-2-pyrrolidinyl)methyl]-4-cyano-1-methoxy-

CBNumber:: CB5402878

Molecular Formula:: C22H27N3O2

Molecular Weight:: 365.47

MOL File:: 149649-22-9.mol

Modify Date:: 2024/10/28 16:48:35

Request For Quotation

N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE Properties

Boiling point	556.6±40.0 °C(Predicted)
Density	1.17±0.1 g/cm3(Predicted)
storage temp.	Desiccate at RT
pka	12.84±0.46(Predicted)

N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE Chemical Properties,Uses,Production

Uses

Nafadotride is a highly potent and competitive dopamine D3 receptor (D3R) antagonist.

Definition

ChEBI: A naphthalenecarboxamide resulting from the formal condensation of the carboxylic acid group of 4-cyano-1-methoxynaphthalene-2-carboxylic acid with the primary amino group of 1-(1-butylpyrrolidin-2-yl]methanamine. It is a highly potent, competitive, prefer ntial dopamine D3 receptor antagonist, centrally active upon systemic administration.

Biological Activity

Highly potent, competitive, preferential dopamine D 3 receptor antagonist. K i values are 0.52, 5, and 269 nM for human cloned D 3 , D 2 and D 4 receptors respectively. Centrally active upon systemic administration.

N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE Suppliers

Global( 34)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CHEMSWORTH	+91-261-2397244	New Delhi, India	6700	30	Inquiry
Aladdin Scientific		United States	52924	58	Inquiry
TargetMol Chemicals Inc.	+8613564774135	United States	19881	58	Inquiry
DAYANG CHEM (HANGZHOU) CO.,LTD	+8617705817739	China	53881	58	Inquiry
TargetMol Chemicals Inc.	4008200310	China	24642	58	Inquiry
Absin Bioscience Inc.	021-38015121-8802	CHINA	6208	58	Inquiry
Abcam Limited	+1 (877) 774-8286	United States	6001	50	Inquiry
ShangHai ChuanQian Chemcial Technique Centre	15869524721	China	4348	58	Inquiry
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	China	8140	58	Inquiry
Wako Pure Chemical Industries, Ltd.	+81 6 6203 3741	Japan	6819	80	Inquiry

Supplier	Advantage
CHEMSWORTH	30
Aladdin Scientific	58
TargetMol Chemicals Inc.	58
DAYANG CHEM (HANGZHOU) CO.,LTD	58
TargetMol Chemicals Inc.	58
Absin Bioscience Inc.	58
Abcam Limited	50
ShangHai ChuanQian Chemcial Technique Centre	58
MedBioPharmaceutical Technology Inc	58
Wako Pure Chemical Industries, Ltd.	80

149649-22-9(N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE)Related Search:

3-CYANOBENZYLAMINE 3-Cyanobenzaldehyde 3-(methylaminomethyl)benzonitrile 3-CYANO-BENZAMIDE 3-Formyl-4-hydroxybenzonitrile

N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE 1-Cyanonaphthalene (-)-N[(N-BUTYL-2-PYRROLIDINYL)METHYL]-1-METHOXY-4-CYANONAPHTHALENE-2-CARBOXAMIDE TARTRATE 4-METHOXY-1-NAPHTHONITRILE

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NAFADOTRIDE N-[(1-BUTYL-2-PYRROLIDINYL)METHYL]-4-CYANO-1-METHOXY-2-NAPHTHALENECARBOXAMIDE 2-Naphthalenecarboxamide, N-[(1-butyl-2-pyrrolidinyl)methyl]-4-cyano-1-methoxy- Nafadotride, D3 antagonist 149649-22-9 C22H27N3O2