SIB 1757

SIB 1757 Structure
CAS No.
31993-01-8
Chemical Name:
SIB 1757
Synonyms
SIB 1757;6-METHYL-2-(PHENYLAZO)-3-PYRIDINOL;6-methyl-2-[(E)-phenyldiazenyl]pyridin-3;(E)-6-Methyl-2-(phenyldiazenyl)pyridin-3-ol;6-Methyl-2-[(E)-phenyldiazenyl]pyridin-3-ol;SIB-1757 6-METHYL-2-(PHENYLAZO)-3-PYRIDINOL;3-Pyridinol, 6-methyl-2-(2-phenyldiazenyl)-;SIB-1757,mGluR,SIB1757,Metabotropic glutamate receptors,inhibit,Inhibitor,SIB 1757
CBNumber:
CB5404317
Molecular Formula:
C12H11N3O
Molecular Weight:
213.24
MOL File:
31993-01-8.mol
Modify Date:
2023/9/20 16:43:00

SIB 1757 Properties

storage temp. Store at RT
solubility DMSO (Slightly), Methanol (Slightly)
form crystalline
color red

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
NFPA 704
0
2 0

SIB 1757 price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) S9186 SIB 1757 ≥99% (HPLC), crystalline 31993-01-8 10MG ₹12221.43 2022-06-14 Buy
Product number Packaging Price Buy
S9186 10MG ₹12221.43 Buy

SIB 1757 Chemical Properties,Uses,Production

Uses

SIB 1757 is an antagonist for mGluR-5.

Biological Activity

A highly selective antagonist for the mGlu 5 metabotropic glutamate receptor subtype; displays an IC 50 value of 0.4 μ M at hmGlu 5 compared with > 30 μ M at hmGlu 1b , hmGlu 2 , hmGlu 4 , hmGlu 6 , hmGlu 7 and hmGlu 8 .

SIB 1757 Preparation Products And Raw materials

Raw materials

Preparation Products

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SIB 1757 Spectrum

SIB 1757 SIB-1757 6-METHYL-2-(PHENYLAZO)-3-PYRIDINOL 6-METHYL-2-(PHENYLAZO)-3-PYRIDINOL 6-Methyl-2-[(E)-phenyldiazenyl]pyridin-3-ol (E)-6-Methyl-2-(phenyldiazenyl)pyridin-3-ol 6-methyl-2-[(E)-phenyldiazenyl]pyridin-3 3-Pyridinol, 6-methyl-2-(2-phenyldiazenyl)- SIB-1757,mGluR,SIB1757,Metabotropic glutamate receptors,inhibit,Inhibitor,SIB 1757 31993-01-8 C12H11N3O Glutamate receptor