JC-1 CHLORIDE
- CAS No.
- Chemical Name:
- JC-1 CHLORIDE
- Synonyms
- JC-1 CHLORIDE;5,5',6,6'-TETRACHLORO-1,1',3,3'-TETRAETHYL-BENZIMIDAZOLYL-CARBOCYANINE CHLORIDE
- CBNumber:
- CB5698178
- Molecular Formula:
- C21H19Cl5N4
- Molecular Weight:
- 504.67
- MOL File:
- Mol file
JC-1 CHLORIDE Chemical Properties,Uses,Production
Uses
JC-1 chloride is a very sensitive fluorescent probe for testing Pgp activity. Capable of distinguishing between resistant, intermediate and sensitve groups, whereas rhodamine 123 only recognizes the resistent group. In cell lines, the red emission band is more convenient for detection of low-level resistance in AML than other probes, such as rhodamine 123 (529nm) or calcein-AM (517nm). Green fluorescent JC-1 existing as a monomer (λem=527nm) at low concentrations or at low membrane potential. However, at higher concentrations (aqueous solutions above 0.1μM) or higher potentials, JC-1 forms red fluorescent ''J-aggregates'', which exhibit a broad excitation spectrum and a very narrow emission spectrum (λem=590nm). JC-1 stains mitochondria in living cells in a membrane potential-dependent funct
JC-1 CHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
JC-1 CHLORIDE Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
A.G. Scientific, Inc. | 858 452 9925 | United States | 1066 | 71 | Inquiry |
Alexis Corporation | +41 61 926 8989 | Switzerland | 3599 | 74 | Inquiry |
Fluorochem Ltd. | +44 1457 868921 | United Kingdom | 6406 | 74 | Inquiry |
Fluorochem Ltd | (01457) 868921 (4 lines) | United Kingdom | 6383 | 65 | Inquiry |
Shanghai Hao Biological Technology Co., Ltd. | 021-58116080 18019263206 | CHINA | 6921 | 58 | Inquiry |
Xiamen Huijia Biological Technology Co., Ltd. | 0592-6020891 | CHINA | 6979 | 58 | Inquiry |
Beijing Fubo Biotechnology Co., Ltd. | 010-57263844 13260236521 | CHINA | 6039 | 58 | Inquiry |
Xiamen Research Biotechnology Co., Ltd. | 0592-6020891 18906011628 | CHINA | 6942 | 58 | Inquiry |
Guangzhou Weijia Technology Co., Ltd. | 020-84224925 18300190102 | CHINA | 6748 | 58 | Inquiry |
Absin Bioscience Inc. | 021-38015121 | CHINA | 6661 | 58 | Inquiry |