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4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER

4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER Structure
CAS No.
191102-87-1
Chemical Name:
4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER
Synonyms
GGTI-2147;GGTI-2147 (GGTI2147);TUQRZGWNDBXSNP-SANMLTNESA-N;Geranylgeranyl transferase inhibitor-2147;4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER;L-Leucine, N-[4-[(1H-imidazol-5-ylmethyl)amino]-2-(1-naphthalenyl)benzoyl]-, methyl ester
CBNumber:
CB5766770
Molecular Formula:
C28H30N4O3
Molecular Weight:
470.56
MOL File:
Mol file
Modify Date:
2023/7/14 17:49:10
Request For Quotation

4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER Properties

Boiling point 710.6±60.0 °C(Predicted)
Density 1.224±0.06 g/cm3(Predicted)
solubility Soluble in DMSO
pka 13.22±0.46(Predicted)
form Solid
Sensitive Light Sensitive & Hygroscopic

4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 345885 GGTI-2147 - CAS 191102-87-1 - Calbiochem A cell-permeable non-thiol peptidomimetic that acts as a potent and selective inhibitor of geranylgeranyltransferase I (GGTase I). 191102-87-1 250μG ₹28660 2022-06-14 Buy
Product number Packaging Price Buy
345885 250μG ₹28660 Buy

4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER Chemical Properties,Uses,Production

Uses

GGTI-2147 is an inhibitors of protein geranylgeranyltransferase-I and protein prenylation. Increases prelamin A accumulation by inhibiting ZMPSTE24 protein in human fibroblast and increases cytosolic accumulation of Rac1 and elicites significant inhibition of GSIS from INS 832/13 cells.

4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER Suppliers

Global( 30)Suppliers
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CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Alpha Biopharmaceuticals Co., Ltd +86-15542445688 China 888 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Nextpeptide Inc +86-0571-81612335 +8613336028439 China 19915 58 Inquiry
United States Biological 800.520.3011 or 781.639.5092 United States 6256 80 Inquiry
Alabiochem Tech.Co., Ltd. 0512-58900862 400-0707518 China 997 59 Inquiry
TargetMol Chemicals Inc. 4008200310 China 23963 58 Inquiry
EMD Biosciences, Inc. 858 450 5500 United States 6529 66 Inquiry
VWR International 800 932 5000 United Kingdom 6554 82 Inquiry
Toronto Research Chemicals +1 (416) 665-9696 Canada 6088 71 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
Alpha Biopharmaceuticals Co., Ltd 58
TargetMol Chemicals Inc. 58
Nextpeptide Inc 58
United States Biological 80
Alabiochem Tech.Co., Ltd. 59
TargetMol Chemicals Inc. 58
EMD Biosciences, Inc. 66
VWR International 82
Toronto Research Chemicals 71
GGTI-2147 4-[[N-(IMIDAZOL-4-YL)METHYLENEAMINO]-2-(1-NAPHTHYL)BENZOYL]LEUCINE METHYL ESTER TUQRZGWNDBXSNP-SANMLTNESA-N GGTI-2147 (GGTI2147) L-Leucine, N-[4-[(1H-imidazol-5-ylmethyl)amino]-2-(1-naphthalenyl)benzoyl]-, methyl ester Geranylgeranyl transferase inhibitor-2147 191102-87-1 A cell-permeable non-thiol peptidomimetic that acts as a potent and selective inhibitor of geranylgeranyltransferase I (GGTase I). Amino Acids & Derivatives, Chiral Reagents, Heterocycles, Inhibitors Other enzyme inhibitors and activators