MAF
- CAS No.
- 101365-54-2
- Chemical Name:
- MAF
- Synonyms
- MAF;C-Maf;4hopcp;4-ho-pcp;MAF power;IFN-γ human;T cell interferon;Immune Interferon;type II interferon;Proto-oncogene c-maf
- CBNumber:
- CB5852420
- Molecular Formula:
- C22H29ClN2O2
- Molecular Weight:
- 388.94
- MOL File:
- Mol file
- Modify Date:
- 2023/5/15 10:43:34
MAF price More Price(2)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | SRP3058 | IFN-γ human Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture | 101365-54-2 | 100μG | ₹40603.8 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | M-200 | Methoxyacetyl fentanyl hydrochloride solution 100?μg/mL in methanol (as free base), certified reference material, ampule of 0.5?mL, Cerilliant? | 101365-54-2 | 0.5ML | ₹10068.1 | 2022-06-14 | Buy |
MAF Chemical Properties,Uses,Production
Uses
IFN-γ (interferon γ)-human has been used for the generation of inflammatory M1 cells from human monocytic cell line, THP1.
General Description
IFN-γ (interferon γ) is an acid-labile glycosylated interferon produced by CD4 and CD8 T lymphocytes as well as activated NK (natural killer) cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC (major histocompatibility complex) proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. The gene is mapped to human chromosome 12q15. Human IFN-γ is species-specific and is biologically active only in human and primate cells. Recombinant human IFN-γ is a 16.7kDa protein containing 143 amino acid residues.
Biochem/physiol Actions
IFN-γ (interferon γ) signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulate the antigen-specific phases of the immune response. It can suppress the generation of anti-inflammatory cytokines and enhance the secretion of proinflammatory cytokines. Additionally, IFN-γ stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK (natural killer) cells and neutrophils. It is responsible for tumor rejection and is capable of killing tumor cells by autophagy or apoptosis. IFN-γ is also involved in Hepatitis E virus disease pathogenesis.
MAF Preparation Products And Raw materials
Raw materials
Preparation Products
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