N-Biotinylaminoethyl Methanethiosulfonate

N-Biotinylaminoethyl Methanethiosulfonate Structure
CAS No.
162758-04-5
Chemical Name:
N-Biotinylaminoethyl Methanethiosulfonate
Synonyms
N-Biotinylaminoethyl methylthiosulphonate;2-[(Biotinoyl)-amino]-ethyl-methanthiosulfonat;MTSEA-Biotin [N-Biotinoylaminoethyl methanethiosulfonate;O-(2-(5-((3AS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)ethyl) methanesulfonothioate;Methanesulfonothioic Acid S-[2-[[5-[(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]iMidazol-4-yl]-1-oxopentyl]aMino]ethyl] Ester
CBNumber:
CB61121786
Molecular Formula:
C13H23N3O4S3
Molecular Weight:
381.53
MOL File:
162758-04-5.mol
Modify Date:
2024/4/1 18:08:31

N-Biotinylaminoethyl Methanethiosulfonate Properties

Melting point 95-103°C
storage temp. -20°C Freezer, Under Inert Atmosphere
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
form A crystalline solid
Stability Moisture Sensitive

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H319-H335-H315
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
HS Code  2934999090
NFPA 704
0
2 0

N-Biotinylaminoethyl Methanethiosulfonate Chemical Properties,Uses,Production

Description

MTSEA-biotin is a thiol-reactive probe that can be used to label proteins at cysteine residues.

Chemical Properties

White Fluffy Solid

Uses

Reacts specifically and rapidly with thiols to form mixed disulfides. N-Biotinylaminoethyl Methanethiosulfonate can be used to probe the structures of the ACh receptor channel of the GABA receptor channel and of lactose permease. MTSEA-biotin has recently been used to probe the topology of the serotonin (5-HT) transporter by site-directed chemical labelling.

N-Biotinylaminoethyl Methanethiosulfonate Preparation Products And Raw materials

Raw materials

Preparation Products

N-Biotinylaminoethyl methylthiosulphonate Methanesulfonothioic Acid S-[2-[[5-[(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]iMidazol-4-yl]-1-oxopentyl]aMino]ethyl] Ester 2-[(Biotinoyl)-amino]-ethyl-methanthiosulfonat MTSEA-Biotin [N-Biotinoylaminoethyl methanethiosulfonate O-(2-(5-((3AS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)ethyl) methanesulfonothioate 162758-04-5 C13H23N3O4S3 Biotin Derivatives Cross Linking Reagents MTS & Sulfhydryl Active Reagents