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PSEUDOLARIC ACID B

PSEUDOLARIC ACID B Structure
CAS No.
82508-31-4
Chemical Name:
PSEUDOLARIC ACID B
Synonyms
PLAB;Pseudolaric acid;Pseudolarix acid B;PSEUDOLARIC ACID B;(-)-Pseudolaric Acid B;Pseudolaric Acid B(PBA);7-Di-O-methylnaringenin;Pseudolaric Acid B (PAB);pha(1e,3e),4-alpha,4a-alpha,9a-alpha)-(-)-(9ci);Pseudolaric acid B, 98%, from Pseudolarix amabilis (J. Nelson) Rehder
CBNumber:
CB6117700
Molecular Formula:
C23H28O8
Molecular Weight:
432.46
MOL File:
82508-31-4.mol
MSDS File:
SDS
Modify Date:
2023/7/28 17:44:41

PSEUDOLARIC ACID B Properties

Melting point 166°C
Boiling point 466.14°C (rough estimate)
Density 1.2108 (rough estimate)
refractive index 1.4480 (estimate)
storage temp. 2-8°C
solubility methanol: soluble1mg/mL, clear, colorless
form powder or crystals
pka 4.52±0.19(Predicted)
color white to off-white
InChIKey VDGOFNMYZYBUDT-YCONPBHISA-N

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06,GHS08
Signal word  Danger
Hazard statements  H301-H361fd
Precautionary statements  P201-P301+P310+P330
Hazard Codes  T
Risk Statements  25-62
Safety Statements  36/37-45-24/25
RIDADR  UN 2811 6.1 / PGIII
WGK Germany  3
HS Code  29329990
NFPA 704
0
2 0

PSEUDOLARIC ACID B price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) L8170 Pseudolaric Acid B ≥98% (HPLC) 82508-31-4 1MG ₹12632.78 2022-06-14 Buy
Sigma-Aldrich(India) L8170 Pseudolaric Acid B ≥98% (HPLC) 82508-31-4 10MG ₹41026.75 2022-06-14 Buy
Product number Packaging Price Buy
L8170 1MG ₹12632.78 Buy
L8170 10MG ₹41026.75 Buy

PSEUDOLARIC ACID B Chemical Properties,Uses,Production

Description

Pseudolaric acid B (PAB) is a diterpene acid isolated from the bark of P. kaempferi, a traditional Chinese medicinal plant. It has reported antifungal activities, consistent with its traditional use in the treatment of dermatological fungal infections. Moreover, PAB has diverse effects that are relevant to cancer therapy, including inducing apoptosis of cancer cells (IC50 = ~1 μM), preventing angiogenesis, and inhibiting tumor growth in vivo.

Uses

(-)-Pseudolaric Acid B is a diterpenoid posessing an immunomodulatory effect. It acts as an immunosuppressant in vitro/vivo however does show some cytotoxicity. Anti-tumor agent as well.

PSEUDOLARIC ACID B Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 195)Suppliers
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Hebei Mojin Biotechnology Co., Ltd +86 13288715578 +8613288715578 China 12459 58 Inquiry
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TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Hubei Ipure Biology Co., Ltd +8613367258412 China 10326 58 Inquiry
Apeloa Pharmaceutical Co., Ltd. +86-0571-87635730 +8615858229168 China 1478 58 Inquiry
Pseudolaric acid Pseudolaric Acid B (PAB) Pseudolaric Acid B(PBA) -1,3-pentadienyl)3,4,4a,5,6,9-hexahydro-3-methyl-1-oxo-,7-methylester,(3-al 1h-4,9a-ethanocyclohepta(c)pyran-7-carboxylicacid,4a-(acetyloxy)-3-(4-carboxy pha(1e,3e),4-alpha,4a-alpha,9a-alpha)-(-)-(9ci) PSEUDOLARIC ACID B PLAB 1H-4,9a-Ethanocyclohepta[c]pyran-7-carboxylicacid,4a-(acetyloxy)-3-[(1E,3E)-4-carboxy-1,3-pentadien-1-yl]-3,4,4a,5,6,9-hexahydro-3-methyl-1-oxo-,7-methyl ester, (3R,4S,4aS,9aR)- Pseudolarix acid B Pseudolaric acid B, 98%, from Pseudolarix amabilis (J. Nelson) Rehder (-)-Pseudolaric Acid B (2E,4E)-5-((3R,4S,4aS,9aS)-4a-acetoxy-7-(methoxycarbonyl)-3-methyl-1-oxo-3,4,4a,5,6,9-hexahydro-1H-4,9a-ethanocyclohepta[c]pyran-3-yl)-2-methylpenta-2,4-dienoic acid 7-Di-O-methylnaringenin (2E,4E)-5-((3R,4S,4aS,9aR)-4a-Acetoxy-7-(methoxycarbonyl)-3-methyl-1-oxo-3,4,4a,5,6,9-hexahydro-1H-4,9a-ethanocyclohepta[c]pyran-3-yl)-2-methylpenta-2,4-dienoic acid 82508-31-4 C23H28O8 chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract Inhibitors