KAHWEOL

KAHWEOL Structure
CAS No.
6894-43-5
Chemical Name:
KAHWEOL
Synonyms
KAHWEOL;Kahweol-RM;KAHWEOL USP/EP/BP;Kahweol, 10 mM in DMSO;Kahweol DISCONTINUED, unstable;Kahweol, Diterpene molecule in coffee beans;(3bS)-3b,4,5,6,7,8,9,10,10aα,10b-Decahydro-7β-hydroxy-10bβ-methyl-5aβ,8β-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol;5a,8-Methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol,3b,4,5,6,7,8,9,10,10a,10b-decahydro-7-hydroxy-10b-methyl-,(3bS,5aS,7R,8R,10aR,10bS)-;[3bS-(3balpha,5abeta,7beta,8beta,10aalpha,10bbeta)]-3b,4,5,6,7,8,9,10,10a,10b-Decahydro-7-hydroxy-10b-methyl-5a,8-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol
CBNumber:
CB6117982
Molecular Formula:
C20H26O3
Molecular Weight:
314.42
MOL File:
6894-43-5.mol
Modify Date:
2025/1/27 9:38:02

KAHWEOL Properties

Melting point 88-90℃
Boiling point 476.6±45.0 °C(Predicted)
Density 1.25±0.1 g/cm3(Predicted)
storage temp. −20°C
solubility DMF:5.0(Max Conc. mg/mL);0.64(Max Conc. mM)
DMSO:18.17(Max Conc. mg/mL);57.77(Max Conc. mM)
Ethanol:5.0(Max Conc. mg/mL);0.64(Max Conc. mM)
Ethanol:PBS (pH 7.2) (1:5):0.02(Max Conc. mg/mL);0.06(Max Conc. mM)
pka 14.43±0.40(Predicted)
form White to off-white solid.
color Off-white to light yellow
LogP 3.380 (est)

KAHWEOL Chemical Properties,Uses,Production

Uses

Kahweol is an antioxidant diterpene contained in unfiltered coffee. Kahweol behaves as an anti-inflammatory and anti-angiogenic compound with potential use in antitumoral therapies. Recent research have demonstrated the ability of Kahweol in inhibiting metastasis by modulating expressions of MMPs and VEGF via STAT3 inactivation.

KAHWEOL Preparation Products And Raw materials

Raw materials

Preparation Products

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TargetMol Chemicals Inc. United States 38630 58 Inquiry
Aladdin Scientific United States 57505 58 Inquiry
Wuhan Huangzhen Biochemical Co., Ltd 13795480948 13795480948 China 4958 58 Inquiry
KAHWEOL (3bS)-3b,4,5,6,7,8,9,10,10aα,10b-Decahydro-7β-hydroxy-10bβ-methyl-5aβ,8β-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol [3bS-(3balpha,5abeta,7beta,8beta,10aalpha,10bbeta)]-3b,4,5,6,7,8,9,10,10a,10b-Decahydro-7-hydroxy-10b-methyl-5a,8-methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol 5a,8-Methano-5aH-cyclohepta[5,6]naphtho[2,1-b]furan-7-methanol,3b,4,5,6,7,8,9,10,10a,10b-decahydro-7-hydroxy-10b-methyl-,(3bS,5aS,7R,8R,10aR,10bS)- KAHWEOL USP/EP/BP Kahweol DISCONTINUED, unstable Kahweol-RM Kahweol, Diterpene molecule in coffee beans Kahweol, 10 mM in DMSO 6894-43-5 6984-43-5 Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals