Chinese english Japanese Germany Korea

PG 501

PG 501 Structure
CAS No.
32891-29-5
Chemical Name:
PG 501
Synonyms
PG 501;Pentona;KAO 264;mazaticol hydrochloride;9-Azabicyclo[3.3.1]nonane, 2-thiopheneacetic acid deriv.;6,6,9-Trimethyl-9-azabicyclo[3.3.1]non-3b-yl a,a-di(2-thienyl)glycolate hydrochloride;6,6,9-Trimethyl-9-azabicyclo[3.3.1]nonan-3b-ol a,a-di-2-thienylglycolate (ester) hydrochloride;Glycolic acid, di-2-thienyl-, 6,6,9-trimethyl-9-azabicyclo[3.3.1]non-3-yl ester hydrochloride, exo- (8CI);2-Thiopheneacetic acid, a-hydroxy-a-2-thienyl-, 6,6,9-trimethyl-9-azabicyclo[3.3.1]non-3-yl ester, hydrochloride, exo-;2-Thiopheneacetic acid, a-hydroxy-a-2-thienyl-, (1R,3R,5R)-6,6,9-trimethyl-9-azabicyclo[3.3.1]non-3-yl ester, hydrochloride, rel- (9CI)
CBNumber:
CB61269985
Molecular Formula:
C21H27NO3S2.HCl
Molecular Weight:
0
MOL File:
32891-29-5.mol
Modify Date:
2023/5/4 17:34:37
Request For Quotation

PG 501 Chemical Properties,Uses,Production

Originator

Pentona, Tanabe ,Japan ,1978

Manufacturing Process

A mixture of 1.0 g of 6,6,9-trimethyl-9-azabicyclo[3.3.1]nonan-3β-ol, methyl α,α-di-(2-thienyl)-glycolate and 30 mg of metallic sodium is heated at 80°C to 90°C for about 2 hours under reduced pressure. After cooling, ether is added to the reaction mixture. The mixture is extracted with 10% hydrochloric acid. The aqueous layer is alkalified with sodium carbonate and reextracted with ethyl acetate. The extract is washed with water, dried and concentrated to dryness. The residue thus obtained is treated with hydrogen chloride by conventional manner. 2.0 g of the α,α-di-(2-thienyl)glycolate of 6,6,9- trimethyl-9-azabicyclo[3.3.1]nonan-3β-ol hydrochloride are obtained. Yield 83%.

Therapeutic Function

Antiparkinsonian

PG 501 Preparation Products And Raw materials

Raw materials

Preparation Products

PG 501 Suppliers

Global( 2)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
HONEST JOY HOLDINGS LIMITED +86-755-26404303 United States 6702 54 Inquiry
Supplier Advantage
TargetMol Chemicals Inc. 58
HONEST JOY HOLDINGS LIMITED 54

32891-29-5(PG 501)Related Search:

Methyl 2,2-dithienylglycolate (1S)-1-(2-THIENYL)ETHANOL Methyl 2-thienylacetate 2-HYDROXY-2,2-BIS(2-THIENYL) ACETIC ACID Ethyl 2-thiopheneacetate
PG 501 2-(Thiophen-2-yl)propan-2-ol (S)-2-(Hydroxyethyl)piperidine hydrochloride (1R)-1-(2-THIENYL)ETHANOL
chevron_left

1of2

chevron_right
2-Thiopheneacetic acid, a-hydroxy-a-2-thienyl-, (1R,3R,5R)-6,6,9-trimethyl-9-azabicyclo[3.3.1]non-3-yl ester, hydrochloride, rel- (9CI) 2-Thiopheneacetic acid, a-hydroxy-a-2-thienyl-, 6,6,9-trimethyl-9-azabicyclo[3.3.1]non-3-yl ester, hydrochloride, exo- 6,6,9-Trimethyl-9-azabicyclo[3.3.1]non-3b-yl a,a-di(2-thienyl)glycolate hydrochloride 6,6,9-Trimethyl-9-azabicyclo[3.3.1]nonan-3b-ol a,a-di-2-thienylglycolate (ester) hydrochloride 9-Azabicyclo[3.3.1]nonane, 2-thiopheneacetic acid deriv. Glycolic acid, di-2-thienyl-, 6,6,9-trimethyl-9-azabicyclo[3.3.1]non-3-yl ester hydrochloride, exo- (8CI) KAO 264 mazaticol hydrochloride PG 501 Pentona 32891-29-5 C21H27NO3S2HCl