Flutrimazole
![Flutrimazole Structure](CAS/GIF/119006-77-8.gif)
- CAS No.
- 119006-77-8
- Chemical Name:
- Flutrimazole
- Synonyms
- Micetal;flutrimazol;FLUTRIMAZOLC;FLUTRIMAZOLE;Flutrimazole CRS;Flutrimazole And Intermediates;1-[(2-Fluorophenyl)(4-fluorophenyl)(phenyl)methyl]imidazole;1-((2-fluorophenyl)(4-fluorophenyl)phenylmethyl)-1h-imidazol;1-[(2-fluorophenyl)-(4-fluorophenyl)phenylmethyl]-1h-imidazole;1-(o-fluoro-alpha-(p-fluorophenyl)-alpha-phenylbenzyl)imidazole
- CBNumber:
- CB6131401
- Molecular Formula:
- C22H16F2N2
- Molecular Weight:
- 346.37
- MOL File:
- 119006-77-8.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:12
Melting point | 161-166℃ |
---|---|
Boiling point | 457.1±40.0 °C(Predicted) |
Density | 1.15±0.1 g/cm3(Predicted) |
storage temp. | -20°C Freezer |
solubility | Practically insoluble in water, freely soluble in tetrahydrofuran, soluble in methanol. |
pka | 6.03±0.34(Predicted) |
form | Solid |
color | White to Pale Yellow |
CAS DataBase Reference | 119006-77-8(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H315-H302-H335-H319 |
Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362 |
HS Code | 2933299090 |
Toxicity | LD50 in male, female mice, male, female rats (mg/kg): >1000, >1000, 808, 1214 orally; >2000, >2000, 1079, 1446 i.p. (Vericat) |
Flutrimazole Chemical Properties,Uses,Production
Description
Flutrimazole, a novel imidazole antifungal launched in Spain, is indicated for mycosis of the skin. Flutrimazole displays potent broad-spectrum of activity against dematophytes, filamentous fungi and yeasts, saprophytic and pathogenic to animals and humans. Similar to other imidazole and triazole antifungals, flutrimazole exerts its biological function through inhibition of fungal lanosterol 14a-demethylase. Excellent local and systemic tolerance of flutrimazole in patients has been reported.
Chemical Properties
White or almost white powder.
Uses
Flutrimazole is a new imidazole antifungal agent with anti-inflammatory properties as well.
Definition
ChEBI: An imidazole antifungal agent that is imidazole in which the hydrogen attached to the nitrogen is replaced by a 2,4'-difluorotrityl group. A topical antifungal agent which displays potent broad-spectrum in vitro activity against dermatophytes, filamentous fungi and yeasts.
Flutrimazole Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Manus Aktteva | +91 (79) 6512-3395 | New Delhi, India | 581 | 34 | Inquiry |
CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
Hebei Xinsheng New Material Technology Co., LTD. | +86-16632316109 | China | 1092 | 58 | Inquiry |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29798 | 60 | Inquiry |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21675 | 55 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29900 | 58 | Inquiry |
Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | China | 6387 | 58 | Inquiry |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
Related articles
- Pharmacodynamics and Toxicity of Flutrimazole
- Flutrimazole is an imidazole derivative with the chemical name 1- [o-fluoro-a-(p-fluorophenyl)-a-phenylbenzyl]imidazole; the c....
- Mar 29,2022
- Flutrimazole - An imidazole antifungal drug
- Flutrimazole, a novel imidazole antifungal launched in Spain, is indicated for mycosis of the skin.
- Oct 15,2019
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