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JACOLINE

JACOLINE Structure
CAS No.
480-76-2
Chemical Name:
JACOLINE
Synonyms
Jacolin;JACOLINE;(20R)-12,15,20-trihydroxy-(15αH)-15,20-dihydro-senecionane-11,16-dione;[1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3,4,5,6,9,11,13,14,14a,14b-decahydro-3,6-dihydroxy-3-[(1R)-1-hydroxyethyl]-5,6-dimethyl-, (3R,5R,6S,14aR,14bR)-
CBNumber:
CB61438381
Molecular Formula:
C18H27NO7
Molecular Weight:
369.41
MOL File:
480-76-2.mol
Modify Date:
2023/7/12 17:04:18
Request For Quotation

JACOLINE Properties

Melting point 221°C
Boiling point 583.5±50.0 °C(Predicted)
Density 1.36±0.1 g/cm3(Predicted)
pka 12.40±0.60(Predicted)

JACOLINE Chemical Properties,Uses,Production

Description

A pyrrolizidine alkaloid which is found in Senecio Jacobea, this base has [α]20D + 48° (CHC13 ) and is hydrolyzed by alkalies to retronecine and jacolinecic acid, ClOH1S0 7. The latter contains three hydroxyl and three methyl groups.

Uses

Jacoline is a potentially carcinogenic, mutagenic, and teratogenic hepatotoxic alkaloid found in the nectar of tansy ragwort (S. jacobaea).

References

Bradbury, Culvenor., Chern. & Ind., 1021 (1954)
Bradbury, Culvenor., Austral. J. Chern., 7,378 (1954)
Bradbury, Willis., ibid, 9,258 (1956)
Geissman" ibid, 12,247 (1959)

JACOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

JACOLINE Suppliers

Global( 18)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Shaanxi Didu New Materials Co. Ltd +86-89586680 +86-13289823923 China 8673 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry
Wuxi Helen Biotechnology Co., Ltd., 0510-85629785 18013409632 China 14081 58 Inquiry
Shanghai Hao Zhun Biological Technology Co., Ltd. 15800340161 CHINA 6846 58 Inquiry
Sichuan BioCrick Biotech Co., Ltd 28-85433893 CHINA 4988 58 Inquiry
United States Biological 800.520.3011 or 781.639.5092 United States 6256 80 Inquiry
Wuhan ChemFaces Biochemical Co., Ltd. 18607101326 15172504745 China 7059 55 Inquiry
TCI (Shanghai) Chemical Trading Co., Ltd. 021-021-61109150 China 31130 58 Inquiry
Foshan Treasure Biotechnology Co., Ltd 0757-85921206 18520245316 China 12664 58 Inquiry
Shanghai Moqi Biological Technology Co., LTD 021-38218169 13341702378 China 9119 58 Inquiry
Supplier Advantage
Shaanxi Didu New Materials Co. Ltd 58
Amadis Chemical Company Limited 58
Wuxi Helen Biotechnology Co., Ltd., 58
Shanghai Hao Zhun Biological Technology Co., Ltd. 58
Sichuan BioCrick Biotech Co., Ltd 58
United States Biological 80
Wuhan ChemFaces Biochemical Co., Ltd. 55
TCI (Shanghai) Chemical Trading Co., Ltd. 58
Foshan Treasure Biotechnology Co., Ltd 58
Shanghai Moqi Biological Technology Co., LTD 58

480-76-2(JACOLINE)Related Search:

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(S)-ALLYL LACTATE JACOLINE DL-LEUCIC ACID ISOPROPYL ESTER 3-PROPOXYPYRROLIDINE
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JACOLINE Jacolin (20R)-12,15,20-trihydroxy-(15αH)-15,20-dihydro-senecionane-11,16-dione [1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3,4,5,6,9,11,13,14,14a,14b-decahydro-3,6-dihydroxy-3-[(1R)-1-hydroxyethyl]-5,6-dimethyl-, (3R,5R,6S,14aR,14bR)- 480-76-2