ChemicalBook > Product Catalog >Biochemical Engineering >Plant extracts >Madecassoside

Madecassoside

CAS No.: 34540-22-2

Chemical Name:: Madecassoside

Synonyms: RederMic;MADECASSOIDE;MADECASSOSIDE;Asiaticoside A;MADECASSOSIDE(P);MADECASSOSIDE hplc;Madecassoside (8CI);MADECASSOSIDE WITH HPLC;Madecassoside (Asiaticoside A);Madecassoside, froM Centella asiatica

CBNumber:: CB6210654

Molecular Formula:: C48H78O20

Molecular Weight:: 975.12

MOL File:: 34540-22-2.mol

Modify Date:: 2024/8/4 20:11:12

Request For Quotation

Madecassoside Properties

Melting point	220-223 °C
Boiling point	1043.6±65.0 °C(Predicted)
Density	1.47±0.1 g/cm3(Predicted)
storage temp.	2-8°C
solubility	H2O: soluble1mg/mL, clear, colorless
pka	12.50±0.70(Predicted)
form	powder
color	white to off-white
Stability	Hygroscopic
InChIKey	BNMGUJRJUUDLHW-CIZDPPTDSA-N
LogP	-1.338 (est)

SAFETY

Risk and Safety Statements

Safety Statements	24/25
WGK Germany	3
RTECS	YU9555000
HS Code	29389090

Madecassoside price More Price(2)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	M6949	Madecassoside from Centella asiatica ≥95% (HPLC)	34540-22-2	10MG	₹16627.2	2022-06-14	Buy
Sigma-Aldrich(India)	M6949	Madecassoside from Centella asiatica ≥95% (HPLC)	34540-22-2	50MG	₹30721.35	2022-06-14	Buy

Product number	Packaging	Price	Buy
M6949	10MG	₹16627.2	Buy
M6949	50MG	₹30721.35	Buy

Madecassoside Chemical Properties,Uses,Production

Description

Madecassoside is a triterpenoid saponin found in the tropical Asian plant C. asiatica. It has a wide range of reported anti-inflammatory, wound healing, and antioxidant activities and has been shown to suppress LPS-induced TNF-α production via inhibition of ERK, p38, and NF-κB activity.

Chemical Properties

Madecassoside is soluble in organic solvents such as ethanol, DMSO, and dimethyl formamide. The solubility of madecassoside in these solvents is approximately 5, 10, and 25 mg/ml, respectively.H2O : 33.33 mg/mL (34.18 mM)

Uses

Madecassoside is an antioxidant and anti-inflammatory agent. Used as a protective agent against cognitive impairment.

Definition

ChEBI: A triterpenoid saponin that is a trisaccharide derivative of madecassic acid. Isolated from Centella asiatica, it exhibits anti-inflammatory, antioxidant and antirheumatic activities.

Mechanism of action

Madecassoside can directly reduce the cytoskeletal protein actin expression of KFs and its mechanism of action is by inhibiting the activity of some (not all) of the several intracellular molecules that are responsible for abnormal keloid migration, including the significant, concentration‐dependent reduction of phosphorylated Akt, PI3K and p38 of KFs and the repression of actin‐depolymerization‐associated p‐cofilin/cofilin[1].

References

[1] Bandopadhyay s, et al. Therapeutic properties and pharmacological activities of asiaticoside and madecassoside: A review. J. Cell. Mol. Med, 2023; 27: 593–608.

Madecassoside Preparation Products And Raw materials

Raw materials

Preparation Products

Madecassoside Suppliers

Global( 294)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
CHEMSWORTH	+91-261-2397244	New Delhi, India	6707	30	Inquiry
Shaanxi Pioneer Biotech Co., Ltd .	+8613259417953	China	3000	58	Inquiry
Shaanxi Dideu Medichem Co. Ltd	+86-29-81148696 +86-15536356810	China	2063	58	Inquiry
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	China	12458	58	Inquiry
Hebei Yanxi Chemical Co., Ltd.	+86-17531190177; +8617531190177	China	5959	58	Inquiry
Shaanxi Haibo Biotechnology Co., Ltd	+undefined18602966907	China	1000	58	Inquiry
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	China	20308	58	Inquiry
Shaanxi TNJONE Pharmaceutical Co., Ltd	+8618740459177	China	1142	58	Inquiry

Supplier	Advantage
A.J Chemicals	58
CLEARSYNTH LABS LTD.	58
CHEMSWORTH	30
Shaanxi Pioneer Biotech Co., Ltd .	58
Shaanxi Dideu Medichem Co. Ltd	58
Hebei Mojin Biotechnology Co., Ltd	58
Hebei Yanxi Chemical Co., Ltd.	58
Shaanxi Haibo Biotechnology Co., Ltd	58
Henan Fengda Chemical Co., Ltd	58
Shaanxi TNJONE Pharmaceutical Co., Ltd	58

Madecassoside Spectrum

Madecassoside(34540-22-2)MS

34540-22-2(Madecassoside)Related Search:

Asiaticoside Centella asiatica extract Total Of Triterpenes PROPYLENE GLYCOL BUTYL ETHER METHYL 13-METHYLTETRADECANOATE

1,12-OCTADECANEDIOL isobutoxypropanol 6-O-BETA-D-GLUCOPYRANOSYL-D-GLUCOPYRANOSE isohexadecanoic acid 2-Ethyl-1,3-hexanediol

MONOLAURIN MONOCAPRYLIN Isopropyl-cyclohexanecarboxylic acid METHYL 15-HYDROXYPENTADECANOATE 15-HYDROXYPENTADECANOIC ACID

N-PENTADECANOIC ACID ETHYL ESTER ETHYL 2,2-DIETHYLBUTYRATE 1,3-DIISOPROPYLCYCLOHEXANE

chevron_left

1of4

chevron_right

MADECASSOIDE MADECASSOSIDE O-6-Deoxy-alpha-L-mannopyranosyl-(1.4)-O-beta-D-glucopyranosyl-(1.6)-beta-D-glucopyranosyl (2alpha,3beta,4alpha,6beta)-2,3,6,23-tetrahydroxyurs-12-en-28-oate O-6-deoxy-alpha-L-mannopyranosyl-(1->4)-O-beta-D-glucopyranosyl-(1->6)-beta-D-glucopyranosyl (2alpha,3beta,4alpha,6beta)-2,3,6,23-tetrahydroxyurs-12-en-28-oate MADECASSOSIDE(P) MADECASSOSIDE hplc Asiaticoside A glucopyranosyl-(1→6)-β-D-glucopyranosyl ester, (2α,3β,4α,6β)- Urs-12-en-28-oicacid, 2,3,6,23-tetrahydroxy-, O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-β-D- 2α,3β,6β,23-Tetrahydroxyurs-12-en-28-oic acid 6-O-[4-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]-β-D-glucopyranosyl ester RederMic MADECASSOSIDE WITH HPLC Madecassoside, froM Centella asiatica Madecassoside, 98%, from Centella asiatica Madecassoside, 98%, from Centella asiatica (L.) Urb. Madecassoside (Asiaticoside A) Urs-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, O-6-deoxy-α-L-mannopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl ester, (2α,3β,4α,6β)- Madecassoside (8CI) (1S,2R,4aS,6aS,6bR,8R,8aR,9R,10R,11R,12aR,12bR,14bS)-(2S,3R,4S,5S,6R)-6-((((2R,3R,4R,5S,6R)-3,4-Dihydroxy-6-(hydroxymethyl)-5-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)methyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl 8,10,11-trihydroxy-9-(hydroxymethyl)-1,2,6a,6b,9,12a-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-4a-carboxylate Centella Asiatica Extract Madecassoside 34540-22-2 C48H78O20 Inhibitors The group of Asiaticoside chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract Saponins