N'-NITROSONORNICOTINE
- CAS No.
- 16543-55-8
- Chemical Name:
- N'-NITROSONORNICOTINE
- Synonyms
- NNN;(2S)-N’nitrosonornicotine;N-NITROSONORNICOTINE;N'-NITROSONORNICOTINE;1’-nitrosonornicotine;N'-NITROSONORNICOTINE;-Nitrosonornicotine-d4;N-nitroso nicotine (NNN);(S)-N’-Nitrosonornicotine
- CBNumber:
- CB6227878
- Molecular Formula:
- C9H11N3O
- Molecular Weight:
- 177.2
- MOL File:
- 16543-55-8.mol
- Modify Date:
- 2023/5/15 10:43:34
| Melting point | 47.1°C |
|---|---|
| Boiling point | 309.13°C (rough estimate) |
| Density | 1.1669 (rough estimate) |
| refractive index | 1.6500 (estimate) |
| storage temp. | Hygroscopic, Refrigerator, Under Inert Atmosphere |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 5.16±0.12(Predicted) |
| color | Off-White to Pale Beige |
| Stability | Stable, but air and light sensitive. Incompatible with oxidizing agents. |
| IARC | 1 (Vol. Sup 7, 89, 100E) 2012 |
| EPA Substance Registry System | N-Nitrosonornicotine (16543-55-8) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P264-P270-P301+P310-P321-P330-P405-P501 |
| Hazard Codes | Xn |
| Risk Statements | 36/37/38-40 |
| Safety Statements | 26-36 |
| RIDADR | 2810 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| Toxicity | LD50 intraperitoneal in mouse: 1gm/kg |
N'-NITROSONORNICOTINE price More Price(1)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | N-075 | (±)-N′-Nitrosonornicotine (NNN) solution 1.0?mg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant? | 16543-55-8 | 1ML | ₹13326.6 | 2022-06-14 | Buy |
| Product number | Packaging | Price | Buy |
|---|---|---|---|
| N-075 | 1ML | ₹13326.6 | Buy |
N'-NITROSONORNICOTINE Chemical Properties,Uses,Production
Description
A nicotine alkaloid, this base has been detected in some Japanese cigarette tobaccos and also in Kirsu tobacco where it occurs in the fresh leaves that have been dried without fermentation. From these two sources it has been isolated at 1.1 and 1. 8 ppm levels respectively
Chemical Properties
white crystals
Uses
A tobacco alkaloid as risk factor of human cancer.
General Description
White crystalline flakes or yellow oil that solidifies on standing in the cold.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
A nitrated amine, nicotine derivative. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
Health Hazard
ACUTE/CHRONIC HAZARDS: When heated to decomposition it may emit toxic and hazardous fumes of NOx and COx.
Fire Hazard
Flash point data for N'-NITROSONORNICOTINE are not available; however, N'-NITROSONORNICOTINE is probably combustible.
Safety Profile
Confirmed carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Low toxicity by intraperitoneal route. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also N-NITROSO COMPOUNDS.
Carcinogenicity
N-Nitrosonornicotine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.
References
Bharadwaj et al., Gann., 66, 585 (1975)
N'-NITROSONORNICOTINE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
| Shanxi Tihondan Pharmaceutical Technology Co., Ltd | +8618235132063 | China | 3725 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
| Shanghai Aladdin Biochemical Technology Co.,Ltd. | +86-18521732826 | China | 48467 | 58 | Inquiry |
| Nantong Hanfang Biotechnology Co. , Ltd. | 18616537568 | China | 30968 | 58 | Inquiry |
| Abosyn | 0512-69561983 13914027025 | China | 3001 | 58 | Inquiry |
| LGC Science (Shanghai) Ltd. | 17717235263 | China | 11572 | 58 | Inquiry |
| https://www.shachemlin.cn/ | 15021879576 | China | 10110 | 58 | Inquiry |
16543-55-8(N'-NITROSONORNICOTINE)Related Search:
1of4
chevron_right