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4-(8-Chloro-6,11-dihydro-11-hydroxy-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-piperidinecarboxylic Acid Ethyl Ester

4-(8-Chloro-6,11-dihydro-11-hydroxy-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-piperidinecarboxylic Acid Ethyl Ester Structure
CAS No.
133284-74-9
Chemical Name:
4-(8-Chloro-6,11-dihydro-11-hydroxy-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-piperidinecarboxylic Acid Ethyl Ester
Synonyms
Loratadine impurity A;Loratadine EP Impurity 1;Loratadine impurity-F(USP);Loratadine Impurity A（EP ）;11-Hydroxy Dihydro Loratadine;Ethyl 4-[(11RS)-8-Chloro-11-hydroxy;Loratadine EP Impurity A ( USP RC F);Loratadine Impurity 1(Loratadine EP Impurity A);Loratidine EP Impurity A/ Loratidine Related Compound F;Loratadine Impurity 1/Loratadine EP Impurity A/11-Hydroxy Dihydroloratadine
CBNumber:
CB62622192
Molecular Formula:
C22H25ClN2O3
Molecular Weight:
400.9
MOL File:
133284-74-9.mol
MSDS File:
SDS
Modify Date:
2023/4/23 13:52:06
Request For Quotation

4-(8-Chloro-6,11-dihydro-11-hydroxy-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-piperidinecarboxylic Acid Ethyl Ester Properties

Melting point >52°C (dec.)
Boiling point 545.1±50.0 °C(Predicted)
Density 1.294
storage temp. -20°C Freezer
solubility Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Slightly), Ethanol (Slightly)
form Solid
pka 12.23±0.20(Predicted)
color White to Pale Yellow

4-(8-Chloro-6,11-dihydro-11-hydroxy-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-piperidinecarboxylic Acid Ethyl Ester Chemical Properties,Uses,Production

Uses

11-Hydroxy Dihydroloratadine is an impurity of Loratadine (L469575).

4-(8-Chloro-6,11-dihydro-11-hydroxy-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-piperidinecarboxylic Acid Ethyl Ester Preparation Products And Raw materials

Raw materials

Preparation Products

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133284-74-9(4-(8-Chloro-6,11-dihydro-11-hydroxy-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-piperidinecarboxylic Acid Ethyl Ester)Related Search:

Desloratadine N-Hydroxypiperidine N-ForMyl Desloratadine 8-Dechloro-7-chloro Loratadine Loratadine Impurity 15 8-Chloro-6,11-dihydro-11-(1-methyl-4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol
Loratadine Impurity 13 Loratadine Impurity 13 Loratadine Impurity 17 3-Hydroxy loratadine 8-Dechloro-10-chloro Loratadine
Loratadine Loratadine 2-Chloro IMpurity N-Methyl Desloratadine 4-chloro-loratadine Loratadine EP Impurity E
8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one N-Carbethoxy-4-piperidone Desloratadine
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11-Hydroxy Dihydro Loratadine 4-(8-Chloro-6,11-dihydro-11-hydroxy-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-piperidinecarboxylic Acid Ethyl Ester 1-Piperidinecarboxylic acid, 4-(8-chloro-6,11-dihydro-11-hydroxy-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-, ethyl ester Loratadine impurity A Loratadine EP Impurity A ( USP RC F) ethyl 4-(8-chloro-11-hydroxy-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridin-11-yl)piperidine-1-carboxylate Loratadine Impurity 1/Loratadine EP Impurity A/11-Hydroxy Dihydroloratadine Loratadine impurity-F(USP) 8-Chloro-6,11-dihydro-11-[N-ethoxycarbonyl-4-piperidinyl]-11-hydroxy-5H-benzo[5,6] cyclohepta[1,2-b]pyridine Loratadine Impurity 1(Loratadine EP Impurity A) Ethyl 4-[(11RS)-8-Chloro-11-hydroxy Ethyl 4-((11RS)-8-chloro-11-hydroxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperid ethyl 4-(8-chloro-11-hydroxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidine-1-carboxylate Loratidine EP Impurity A/ Loratidine Related Compound F Loratadine Impurity A（EP ） Ethyl 4-(8-chloro-11-hydroxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidine-1-carboxylate (Loratadine Impurity) Loratadine EP Impurity 1 133284-74-9 Amines Heterocycles Impurities Intermediates & Fine Chemicals Pharmaceuticals Amines, Heterocycles, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals