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Revefenacin

CAS No.: 864750-70-9

Chemical Name:: Revefenacin

Synonyms: Revefenacin;TD-4208;1-(2-(4-((4-carbamoylpiperidin-1-yl)methyl)-N-methylbenzamido)ethyl)piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate;CPDD1221;REVENACIN;GSK1160724;Raffinazine;TD 4208;TD4208;Revefenacin Crude;Revefenacin / TD4208

CBNumber:: CB63054398

Molecular Formula:: C35H43N5O4

Molecular Weight:: 597.75

MOL File:: 864750-70-9.mol

Modify Date:: 2024/7/2 8:55:13

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Revefenacin Properties

Boiling point	777.5±60.0 °C(Predicted)
Density	1.26±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO : ≥ 125 mg/mL (209.12 mM)
form	Solid
pka	13.34±0.70(Predicted)
color	White to off-white
InChIKey	FYDWDCIFZSGNBU-UHFFFAOYSA-N
SMILES	C(OC1CCN(CCN(C(=O)C2=CC=C(CN3CCC(C(N)=O)CC3)C=C2)C)CC1)(=O)NC1=CC=CC=C1C1=CC=CC=C1

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P280-P301+P312-P302+P352-P305+P351+P338

Revefenacin Chemical Properties,Uses,Production

Application

Revefenacin is an FDA-approved anticholinergic drug, a new tertiary amine biphenylcarbamate agent that also belongs to the long-acting muscarinic antagonist (LABA) family. It has the effect of relaxing the muscles around the airways of the lungs to make breathing easier. The structurally unstable tertiary amide produces a "soft drug" site, allowing rapid systemic clearance and minimising systemically mediated adverse effects. It can be used to treat symptoms such as wheezing, shortness of breath, cough and chest tightness in patients with chronic obstructive pulmonary disease (COPD: a group of diseases affecting the lungs and airways, including chronic bronchitis and emphysema).

Revefenacin Preparation Products And Raw materials

Raw materials

1-(2-(3-formyl-N-methylbenzamido)ethyl)piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate Isonipecotamide

Preparation Products

Revefenacin Suppliers

Global( 129)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
SKVen Technologies Pvt.Ltd.	+91-7032295152 +91-7032295152	Hyderabad, India	81	58	Inquiry
Maithri Drugs Pvt Ltd	+91-9059204566 +91-9848881740	Telangana, India	64	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
SynZeal Research Pvt Ltd	+1 226-802-2078	Gujarat, India	6522	58	Inquiry
Chengdu Aupone Pharmaceutical Co.Ltd.	+86-28-+86-28-87843998-6060-6060 +8618631098571	China	48	58	Inquiry
Hangzhou ICH Biofarm Co., Ltd	+86-0571-28186870; +undefined8613073685410	China	985	58	Inquiry
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8617865335152	China	10978	58	Inquiry
Biopole Pharmatech Co., Ltd.	+8615151475053	China	37	58	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32760	60	Inquiry

Supplier	Advantage
SKVen Technologies Pvt.Ltd.	58
Maithri Drugs Pvt Ltd	58
CLEARSYNTH LABS LTD.	58
Pharmaffiliates Analytics and Synthetics P. Ltd	58
SynZeal Research Pvt Ltd	58
Chengdu Aupone Pharmaceutical Co.Ltd.	58
Hangzhou ICH Biofarm Co., Ltd	58
Zibo Hangyu Biotechnology Development Co., Ltd	58
Biopole Pharmatech Co., Ltd.	58
ATK CHEMICAL COMPANY LIMITED	60

How to synthesize Revefenacin?
Revefenacin is a new M3 muscarinic receptor antagonist, which could prevent acetylcholine from binding with the muscarinic rec....
Dec 22，2023

864750-70-9(Revefenacin)Related Search:

Kanamycin sulfate Dimethoxymethane ZVPVPYWMFMUFEZ-UHFFFAOYSA-N 1-(2-(methylamino)ethyl)piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate 1-(4-PIPERIDINYLCARBONYL)-4-PIPERIDINECARBOXYLIC ACID

1-(2-(methylamino)ethyl)piperidin-4-ol hydrochloride(WX191324S1) (Dimethylamino)acetaldehyde Dimethyl Acetal Carbamic acid, N-[1,1'-biphenyl]-2-yl-, 1-methyl-4-piperidinyl ester 1221

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GSK1160724 CPDD1221 Revefenacin / TD4208 Revefenacin:TD-4208:GSK-1160724 biphenyl-2-ylcarbamic acid 1-(2-{[4-(4-carbamoylpiperidin-1-ylmethyl)benzoyl]methylamino}ethyl)piperidin-4-ylester TD 4208;TD4208 1-[2-[[4-[(4-carbamoylpiperidin-1-yl)methyl]benzoyl]-methylamino]ethyl]piperidin-4-yl] N-(2-phenylphenyl)carbamate Carbamic acid, N-[1,1'-biphenyl]-2-yl-, 1-[2-[[4-[[4-(aminocarbonyl)-1-piperidinyl]methyl]benzoyl]methylamino]ethyl]-4-piperidinyl ester TD-4208 Revefenacin 1-(2-(4-((4-carbamoylpiperidin-1-yl)methyl)-N-methylbenzamido)ethyl)piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate REVENACIN Raffinazine 1-[2-[[4-[[4-(Aminocarbonyl)-1-piperidinyl]methyl]benzoyl]methylamino]ethyl]-4-piperidinyl N-[1,1′-biphenyl]-2-ylcarbamate Revefenacin Crude 1-(2-(4-((4-Carbamoylpiperidin-1-yl)methyl)-N-methylbenzamido)ethyl)piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate 1-(2-(3-((4-carbamoylpiperidin-1-yl)methyl)-N-methylbenzamido)ethyl)piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate 864750-70-9 C35H43N5O4