CL 218872

CAS No.: 66548-69-4

Chemical Name:: CL 218872

Synonyms: CI 218872;CL 218872;3-METHYL-6-(3-(TRIFLUOROMETHYL)PHENYL)*1 ,2,4-TRIAZO;3-Methyl-6-(3-(trifluoromethyl)phenyl)-1,2,4-triazolo(4,2-B)pyridazine;3-Methyl-6-[3-(trifluoromethyl)phenyl]-1,2,4-triazolo[4.3-6] pyridazine;3-METHYL-6-(3-[TRIFLUOROMETHYL]PHENYL)-1,2,4-TRIAZOLO-(4,3-B)PYRIDAZINE;1,2,4-Triazolo(4,3-B)pyridazine, 3-methyl-6-(3-(trifluoromethyl)phenyl)-;GABA Receptor,Gamma-aminobutyric acid Receptor,CL218872,CL 218872,γ-Aminobutyric acid Receptor,Inhibitor,inhibit,CL-218872

CBNumber:: CB6312273

Molecular Formula:: C13H9F3N4

Molecular Weight:: 278.23

MOL File:: 66548-69-4.mol

Modify Date:: 2024/7/2 8:55:13

Request For Quotation

CL 218872 Properties

Melting point	193-194 °C(Solv: methanol (67-56-1))
Density	1.43±0.1 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMF: 1 mg/ml; DMSO: 1 mg/ml; Ethanol: 1 mg/ml
form	A solid
pka	0.48±0.30(Predicted)
color	Light yellow to brown

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36

WGK Germany

NFPA 704

	0
2		0

CL 218872 Chemical Properties,Uses,Production

Uses

CL 218872 is a benzodiazepine receptor (BZR) partial agonist and a putative anxiolytic.

Biological Activity

Benzodiazepine agonist displaying selectivity for α 1 subunit-containing GABA A receptors (K i values are 130, 1820, 1530, > 10000, 490 and > 10000 nM for α 1, α 2, α 3, α 4, α 5 and α 6-subunit containing receptors respectively). Orally active anxiolytic and anticonvulsant in vivo .

CL 218872 Preparation Products And Raw materials

Raw materials

Preparation Products

CL 218872 Suppliers

Global( 56)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
Nanjing Doge Biomedical Technology Co., Ltd	+86-25-58227606 +86-15305155328	China	4128	58	Inquiry
Golden Pharma Co., Limited	+undefined18958062155	China	5905	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354	United States	19973	58	Inquiry
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971 +86-17331933971	China	2503	58	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	57511	58	Inquiry
Amadis Chemical Company Limited	571-89925085	China	131980	58	Inquiry
Shanghai Yuda Industrial Co., Ltd.	021-64133189 13788995069	CHINA	6107	58	Inquiry
Shanghai Weiwei Biological Technology Co., Ltd.	021-55669583 18616258598	CHINA	4398	58	Inquiry
Shanghai Haoyang Biological Technology Co., Ltd.	021-54046790 15121098156	CHINA	2905	58	Inquiry

Supplier	Advantage
CLEARSYNTH LABS LTD.	58
Nanjing Doge Biomedical Technology Co., Ltd	58
Golden Pharma Co., Limited	58
TargetMol Chemicals Inc.	58
Henan Bao Enluo International TradeCo.，LTD	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58
Shanghai Yuda Industrial Co., Ltd.	58
Shanghai Weiwei Biological Technology Co., Ltd.	58
Shanghai Haoyang Biological Technology Co., Ltd.	58

66548-69-4(CL 218872)Related Search:

4-AMINO-3,5-DIMETHYL-1,2,4-TRIAZOLE CL 218872

3-METHYL-6-(3-(TRIFLUOROMETHYL)PHENYL)*1 ,2,4-TRIAZO 1,2,4-Triazolo(4,3-B)pyridazine, 3-methyl-6-(3-(trifluoromethyl)phenyl)- 3-Methyl-6-(3-(trifluoromethyl)phenyl)-1,2,4-triazolo(4,2-B)pyridazine CL 218872 3-METHYL-6-(3-[TRIFLUOROMETHYL]PHENYL)-1,2,4-TRIAZOLO-(4,3-B)PYRIDAZINE CI 218872 3-Methyl-6-[3-(trifluoromethyl)phenyl]-1,2,4-triazolo[4.3-6] pyridazine GABA Receptor,Gamma-aminobutyric acid Receptor,CL218872,CL 218872,γ-Aminobutyric acid Receptor,Inhibitor,inhibit,CL-218872 66548-69-4