2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid

2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid Structure
CAS No.
74936-81-5
Chemical Name:
2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid
Synonyms
Benidipine Impurity E;Nimodipine Impurity 8;Nicardipine Impurity 28;Lercanidipine Impurity 10;Benidipine Impurity E(Nimodipine Impurity 7);2-methoxyethyl (E)-2-benzylidene-3-oxobutanoate;2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid;3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-
CBNumber:
CB63128336
Molecular Formula:
C15H14N2O6
Molecular Weight:
318.28
MOL File:
74936-81-5.mol
MSDS File:
SDS
Modify Date:
2024/4/25 17:59:01

2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid Properties

Boiling point 538.9±50.0 °C(Predicted)
Density 1.436±0.06 g/cm3(Predicted)
pka 1.38±0.70(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P280-P305+P351+P338-P321
HS Code  2933399990

2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid Chemical Properties,Uses,Production

Uses

2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic Acid is used in the preparation of benidipine hydrochloride metabolites. Benidipine is a highly potent and long-?acting Calcium antagonist now under study as an antihypertensive and as an antianvginal agent.

2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 2-methoxyethyl (E)-2-benzylidene-3-oxobutanoate Lercanidipine Impurity 10 Benidipine Impurity E Nimodipine Impurity 8 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)- Nicardipine Impurity 28 Benidipine Impurity E(Nimodipine Impurity 7) 74936-81-5