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1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(1-methylethyl) ester

CAS No.: 21881-78-7

Chemical Name:: 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(1-methylethyl) ester

Synonyms: Nimodipine EP Imp B;Nimodipine Impurity 2;Nilvadipine Impurity D;Nilvadipine Impurity 4;Nitrendipine Impurity 8;Nimodipine EP Impurity B;Nitrendipine Impurity1224;Nimodipine Impurity B Control;Bis(1-methylethyl) 2,6-Dimethyl-4-(;Nimodipine EP Impurity B(Nitrendipine Impurity1224)

CBNumber:: CB82717263

Molecular Formula:: C21H26N2O6

Molecular Weight:: 402.44

MOL File:: 21881-78-7.mol

Modify Date:: 2024/4/22 15:07:34

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1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(1-methylethyl) ester Properties

Melting point	123-125℃ (ethanol )
Boiling point	512.1±50.0 °C(Predicted)
Density	1.186±0.06 g/cm3(Predicted)
storage temp.	Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility	Chloroform (Slightly), Methanol (Slightly)
form	Solid
pka	2.94±0.70(Predicted)
color	Pale Beige
Stability	Hygroscopic

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(1-methylethyl) ester Chemical Properties,Uses,Production

Uses

3-Des(2-methoxyethyl) 3-(1-Methylethyl) Ester Nimodipine (Nimodipine EP Impurity B) can be used in synthetic preparation of dihydropyridinedicarboxylic acid esters by methylimidazolium trifluoroacetate-catalyzed Hantzsch cyclocondensation reaction of oxo-carboxylic acid esters with aldehydes and ammonium acetate. It can also be used as an analyte for analytical study in developing and optimizing a validated isocratic reversed-phase high-performance liquid chromatograhy separation of nimodipine and impurities in tablets using experimental. design methodology. It is an impurity of the drug Nimodipine (N478200).

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(1-methylethyl) ester Preparation Products And Raw materials

Raw materials

Preparation Products

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(1-methylethyl) ester Suppliers

Global( 58)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
SynZeal Research Pvt Ltd	+1 226-802-2078	Gujarat, India	6522	58	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	China	30253	58	Inquiry
sgtlifesciences pvt ltd	+8617013299288	China	12382	58	Inquiry
China National Standard Pharmaceutical Corporation Limited	+8615391658522	China	11927	58	Inquiry
ShenZhen H&D Pharmaceutical Technology Co., LTD	+86-0755-22677845 +86-13627253706	China	3031	58	Inquiry
Guangzhou PI PI Biotech Inc	+86-020-81716320 +86-13602409664	China	3635	55	Inquiry
Hubei De'ao Chemical Research Pharmaceutical Technology Co., Ltd	18502726233; 18502726233	China	9486	58	Inquiry
Shanghai Kewel Chemical Co., Ltd.	021-64609169 18901607656	China	9911	50	Inquiry

Supplier	Advantage
CLEARSYNTH LABS LTD.	58
SynZeal Research Pvt Ltd	58
Pharmaffiliates Analytics and Synthetics P. Ltd	58
Career Henan Chemica Co	58
sgtlifesciences pvt ltd	58
China National Standard Pharmaceutical Corporation Limited	58
ShenZhen H&D Pharmaceutical Technology Co., LTD	58
Guangzhou PI PI Biotech Inc	55
Hubei De'ao Chemical Research Pharmaceutical Technology Co., Ltd	58
Shanghai Kewel Chemical Co., Ltd.	50

21881-78-7(1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(1-methylethyl) ester)Related Search:

Nimodipine Impurity 16 (Z)-3-aminobut-2-enamide 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid Nimodipine Impurity 15 Nimodipine Impurity 6

1-Boc-hexahydro-1,4-diazepine Nimodipine Nimodipine Impurity 4 NIMODIPINE RELATED COMPOUND A (50 MG) (2-METHOXYETHYL 1-METHYLETHYL 2,6-DIMETHYL-4-(3-NITROPHENYL)PYRIDINE-3,5-DICARBOXYLATE) NIMODIPINE RELATED COMPOUND B (50 MG) (BIS(2-METHOXYETHYL) 2,6-DIMETHYL-4-(3-NITROPHE-NYL)-1,4-DIHYDROPYRIDINE-3,5-DICARBOXYLATE) (AS)

Nimodipine Impurity 5

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1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(1-methylethyl) ester Nimodipine EP Impurity B (RS)-Di-iso-propyl-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate Bis(1-methylethyl) 2,6-Dimethyl-4-( Nimodipine Impurity B Control 3,5-diisopropyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate Nimodipine EP Imp B Nimodipine Impurity 2 3-Des(2-methoxyethyl) 3-(1-Methylethyl) Ester Nimodipine Bis(1-methylethyl) 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate Nitrendipine Impurity1224 diisopropyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate Nitrendipine Impurity 8 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3,5-bis(1-methylethyl) ester Nilvadipine Impurity D Diisopropyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate (Nimodipine Impurity) Nimodipine EP Impurity B(Nitrendipine Impurity1224) Nilvadipine Impurity 4 21881-78-7