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ChemicalBook > Product Catalog >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(1-methylethyl) ester

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(1-methylethyl) ester

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(1-methylethyl) ester Structure
CAS No.
21881-78-7
Chemical Name:
1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(1-methylethyl) ester
Synonyms
Nimodipine EP Imp B;Nimodipine Impurity 2;Nilvadipine Impurity D;Nilvadipine Impurity 4;Nitrendipine Impurity 8;Nimodipine EP Impurity B;Nitrendipine Impurity1224;Nimodipine Impurity B Control;Bis(1-methylethyl) 2,6-Dimethyl-4-(;Nimodipine EP Impurity B(Nitrendipine Impurity1224)
CBNumber:
CB82717263
Molecular Formula:
C21H26N2O6
Molecular Weight:
402.44
MOL File:
21881-78-7.mol
Modify Date:
2025/1/27 9:38:02
Request For Quotation

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(1-methylethyl) ester Properties

Melting point 123-125℃ (ethanol )
Boiling point 512.1±50.0 °C(Predicted)
Density 1.186±0.06 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka 2.94±0.70(Predicted)
color Pale Beige
Stability Hygroscopic

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(1-methylethyl) ester Chemical Properties,Uses,Production

Uses

3-Des(2-methoxyethyl) 3-(1-Methylethyl) Ester Nimodipine (Nimodipine EP Impurity B) can be used in synthetic preparation of dihydropyridinedicarboxylic acid esters by methylimidazolium trifluoroacetate-catalyzed Hantzsch cyclocondensation reaction of oxo-carboxylic acid esters with aldehydes and ammonium acetate. It can also be used as an analyte for analytical study in developing and optimizing a validated isocratic reversed-phase high-performance liquid chromatograhy separation of nimodipine and impurities in tablets using experimental. design methodology. It is an impurity of the drug Nimodipine (N478200).

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(1-methylethyl) ester Preparation Products And Raw materials

Raw materials

Preparation Products

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(1-methylethyl) ester Suppliers

Global( 70)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6257 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6514 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6739 58 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30231 58 Inquiry
CR Corporation Limited +8613062833949 China 8647 58 Inquiry
sgtlifesciences pvt ltd +8617013299288 China 12373 58 Inquiry
China National Standard Pharmaceutical Corporation Limited +8615391658522 China 11922 58 Inquiry
ShenZhen H&D Pharmaceutical Technology Co., LTD +8618627948422 China 3619 58 Inquiry
Guangzhou CATO Research Chemicals Inc. +86-020-81960175-617 +8615602392859 China 6335 58 Inquiry
QUALITY CONTROL SOLUTIONS LTD. 0755-66853366; 13670046396 China 24342 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
SynZeal Research Pvt Ltd 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
Career Henan Chemica Co 58
CR Corporation Limited 58
sgtlifesciences pvt ltd 58
China National Standard Pharmaceutical Corporation Limited 58
ShenZhen H&D Pharmaceutical Technology Co., LTD 58
Guangzhou CATO Research Chemicals Inc. 58
QUALITY CONTROL SOLUTIONS LTD. 58

21881-78-7(1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(1-methylethyl) ester)Related Search:

Nimodipine Impurity 16 (Z)-3-aminobut-2-enamide 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid Nimodipine Impurity 15 Nimodipine Impurity 6
1-Boc-hexahydro-1,4-diazepine Nimodipine Nimodipine Impurity 4 NIMODIPINE RELATED COMPOUND A (50 MG) (2-METHOXYETHYL 1-METHYLETHYL 2,6-DIMETHYL-4-(3-NITROPHENYL)PYRIDINE-3,5-DICARBOXYLATE) NIMODIPINE RELATED COMPOUND B (50 MG) (BIS(2-METHOXYETHYL) 2,6-DIMETHYL-4-(3-NITROPHE-NYL)-1,4-DIHYDROPYRIDINE-3,5-DICARBOXYLATE) (AS)
Nimodipine Impurity 5
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1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(1-methylethyl) ester Nimodipine EP Impurity B (RS)-Di-iso-propyl-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate Bis(1-methylethyl) 2,6-Dimethyl-4-( Nimodipine Impurity B Control 3,5-diisopropyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate Nimodipine EP Imp B Nimodipine Impurity 2 3-Des(2-methoxyethyl) 3-(1-Methylethyl) Ester Nimodipine Bis(1-methylethyl) 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate Nitrendipine Impurity1224 diisopropyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate Nitrendipine Impurity 8 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3,5-bis(1-methylethyl) ester Nilvadipine Impurity D Diisopropyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate (Nimodipine Impurity) Nimodipine EP Impurity B(Nitrendipine Impurity1224) Nilvadipine Impurity 4 21881-78-7