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4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide

4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide Structure
CAS No.
915087-16-0
Chemical Name:
4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide
Synonyms
EZLA-API;Desfluoroenzalutamide;Defluoro-enzalutamide;Enzalutamide Impurity 5;Enzalutamide Des Fluoro-EZD;Enzalutamide Desfluoro impurity;Enzalutamide Impurity I/ Enzalutamide Desfluoro impurity;4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide;Benzamide, 4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-N-methyl-;4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-N-methylbenzamide
CBNumber:
CB63154988
Molecular Formula:
C21H17F3N4O2S
Molecular Weight:
446.45
MOL File:
915087-16-0.mol
Modify Date:
2023/5/15 10:44:02
Request For Quotation

4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide Properties

Density 1.46±0.1 g/cm3(Predicted)
solubility Acetone (Slightly), Chloroform (Slightly)
pka 14.46±0.46(Predicted)
form Solid
color Pale Yellow to Light Yellow

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07,GHS08
Signal word  Danger
Hazard statements  H302-H360
Precautionary statements  P264-P270-P301+P312-P330-P501

4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide Chemical Properties,Uses,Production

Uses

Defluoro-MDV 3100 (Defluoro-enzalutamide) is an impurity of Enzalutamide (M199800), which is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. Enzalutamide has been shown to induce tumor cell apoptosis, and is used for the treatment of castration-resistant prostate cancer.

4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide Preparation Products And Raw materials

Raw materials

Preparation Products

4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide Suppliers

Global( 58)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Chemicea Pharmaceuticals Pvt Ltd +91-918482849343 +91-8482849343 Mumbai, India 461 58 Inquiry
Varanous Labs Pvt Ltd +91-7036248882 +91-7036248882 Hyderabad, India 1541 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Shanghai Daken Advanced Materials Co.,Ltd +86-371-66670886 China 16220 58 Inquiry
sgtlifesciences pvt ltd +8617013299288 China 12382 58 Inquiry
China National Standard Pharmaceutical Corporation Limited +8615391658522 China 11927 58 Inquiry
Sichuan HongRi Pharma-Tech Co.,Ltd +86-028-64841719 +8617390183901 China 1358 58 Inquiry
Jilin Chinese Academy of Sciences-yanshen Technology +undefined18143011203 China 42057 58 Inquiry
Supplier Advantage
Chemicea Pharmaceuticals Pvt Ltd 58
Varanous Labs Pvt Ltd 58
CLEARSYNTH LABS LTD. 58
SynZeal Research Pvt Ltd 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
Shanghai Daken Advanced Materials Co.,Ltd 58
sgtlifesciences pvt ltd 58
China National Standard Pharmaceutical Corporation Limited 58
Sichuan HongRi Pharma-Tech Co.,Ltd 58
Jilin Chinese Academy of Sciences-yanshen Technology 58

915087-16-0(4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide)Related Search:

Enzalutamide Impurity 20 4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluorobenzoic acid methyl ester Enzalutamide EnzalutaMide IMpurity methyl 2-fluoro-4-((1-methoxy-2-methyl-1-oxopropan-2-yl)amino)benzoate
4-Bromo-2-fluorobenzoic acid 4-[3-[4-Cyano-3-(trifluoroMethyl)phenyl]-5,5-diMethyl-4-oxo-2-thioxo-1-iMidazolidinyl]-2-fluoro-N-(Methyl-d3)benzaMide Enzalutamide Methyl 4-bromo-2-fluorobenzoate 4-(2-CYANOPROPAN-2-YLAMINO)-2-FLUORO-N-METHYLBENZAMIDE
Enzalutamide carboxylic acid N-desMethyl EnzalutaMide [2H6]-Enzalutamide Enzalutamide Impurity 7 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile
Enzalutamide Impurity 7 4-[1-(4-cyano-3-trifluoromethyl-phenylcarbamoyl)-1-methyl-ethylamino]-2-fluoro-N- 4-amino-2-fluoro-N-methylbenzamide
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4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide Enzalutamide Impurity 5 Defluoro-enzalutamide 4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-N-methylbenzamide Enzalutamide Des Fluoro-EZD Desfluoroenzalutamide Enzalutamide Desfluoro impurity Enzalutamide Impurity I/ Enzalutamide Desfluoro impurity EnzalutamideImpurityIQ: What is EnzalutamideImpurityI Q: What is the CAS Number of EnzalutamideImpurityI Q: What is the storage condition of EnzalutamideImpurityI Q: What are the applications of EnzalutamideImpurityI Benzamide, 4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-N-methyl- 4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-N-methylbenzamide? (Enzalutamide Impurity） EZLA-API 915087-16-0