Argatroban Impurity 23
- CAS No.
- 1356847-56-7
- Chemical Name:
- Argatroban Impurity 23
- Synonyms
- [2H3]-Argatroban;Argatroban-d3 (hydrochloride);Argatroban-d3 (Mixture Of Diastereomers)
- CBNumber:
- CB63359002
- Molecular Formula:
- C23H33D3N6O5S
- Molecular Weight:
- 511.652625334
- MOL File:
- 1356847-56-7.mol
- Modify Date:
- 2023/5/21 10:59:17
Argatroban Impurity 23 Chemical Properties,Uses,Production
Description
Argatroban-d3 is intended for use as an internal standard for the quantification of argatroban by GC- or LC-MS. Argatroban is a reversible inhibitor of thrombin (IC50s = 0.01 and 0.09 μM for the free and clot-bound forms, respectively). It is selective for thrombin over factor Xa, trypsin, plasmin, and tissue plasminogen activator (Kis = 0.0045, 53, 0.19, 25.7, and 87.7 μM, respectively). It inhibits thrombin-induced platelet aggregation in washed isolated guinea pig platelets with an IC50 value of 0.077 μM. Argatroban (3.2 mg/kg, s.c.) decreases thrombus formation in a guinea pig model of iron chloride-induced arterial thrombosis. Formulations containing argatroban have been used in the prevention or treatment of thrombosis in patients with heparin-induced thrombocytopenia.
Argatroban Impurity 23 Preparation Products And Raw materials
Raw materials
Preparation Products
Argatroban Impurity 23 Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
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CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
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Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | China | 10991 | 58 | Inquiry |
Shandong Mopai Biotechnology Co., Ltd | 13070690626 13053322091 | China | 11056 | 58 | Inquiry |
Hubei Ruinuo Pharmaceutical Technology Co., Ltd | 13165688766 | China | 5000 | 58 | Inquiry |
QUALITY CONTROL SOLUTIONS LTD. | 13670046396 | China | 18899 | 58 | Inquiry |
Hubei Qingbei Yunyan Pharmaceutical Technology Co., Ltd | 18162595016; 18162595016 | China | 9117 | 58 | Inquiry |
Nanjing Shizhou Biology Technology Co.,Ltd | 17301488900 | China | 12582 | 58 | Inquiry |
Shanghai Hao Zhun Biological Technology Co., Ltd. | 15800340161 | CHINA | 6846 | 58 | Inquiry |
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