Argatroban Impurity 23

Argatroban Impurity 23 구조식 이미지
카스 번호:
1356847-56-7
상품명:
Argatroban Impurity 23
동의어(영문):
[2H3]-Argatroban;Argatroban-d3 (hydrochloride);Argatroban-d3 (Mixture Of Diastereomers)
CBNumber:
CB63359002
분자식:
C23H33D3N6O5S
포뮬러 무게:
511.652625334
MOL 파일:
1356847-56-7.mol

Argatroban Impurity 23 속성

저장 조건
Store at -20°C
용해도
DMF: soluble,DMSO: soluble,Methanol: soluble
물리적 상태
고체

안전

Argatroban Impurity 23 C화학적 특성, 용도, 생산

개요

Argatroban-d3 is intended for use as an internal standard for the quantification of argatroban by GC- or LC-MS. Argatroban is a reversible inhibitor of thrombin (IC50s = 0.01 and 0.09 μM for the free and clot-bound forms, respectively). It is selective for thrombin over factor Xa, trypsin, plasmin, and tissue plasminogen activator (Kis = 0.0045, 53, 0.19, 25.7, and 87.7 μM, respectively). It inhibits thrombin-induced platelet aggregation in washed isolated guinea pig platelets with an IC50 value of 0.077 μM. Argatroban (3.2 mg/kg, s.c.) decreases thrombus formation in a guinea pig model of iron chloride-induced arterial thrombosis. Formulations containing argatroban have been used in the prevention or treatment of thrombosis in patients with heparin-induced thrombocytopenia.

Argatroban Impurity 23 준비 용품 및 원자재

원자재

준비 용품


Argatroban Impurity 23 공급 업체

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