10-Gingerol
- CAS No.
- 23513-15-7
- Chemical Name:
- 10-Gingerol
- Synonyms
- 10-GINGEROL;GINGEROL, 10-;10-Gingerol ,98%;10-GINGEROL, HPLC 98%;(+)-(S)-[10]-Gingerol;10-Gingerol USP/EP/BP;[10]-Gingerol Standard;10]-Gingerol >=95% (HPLC);Propionic Acid Impurity 1;10-Gingerol, 98%, from Zingiber officinale Roscoe
- CBNumber:
- CB6399377
- Molecular Formula:
- C21H34O4
- Molecular Weight:
- 350.49
- MOL File:
- 23513-15-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:14
| Melting point | 56-58 °C |
|---|---|
| Boiling point | 499.7±35.0 °C(Predicted) |
| Density | 1.037±0.06 g/cm3(Predicted) |
| Flash point | 166℃ |
| storage temp. | 2-8°C |
| solubility | methanol: soluble5mg/mL, clear, colorless |
| form | Solid |
| pka | 10.02±0.20(Predicted) |
| color | Yellow |
| Water Solubility | practically insoluble in water |
| InChIKey | AIULWNKTYPZYAN-SFHVURJKSA-N |
| LogP | 4.900 (est) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| Risk Statements | 53 |
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| HS Code | 29145019 |
10-Gingerol price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | G5798 | [10]-Gingerol ≥98% (HPLC) | 23513-15-7 | 5MG | ₹25027.4 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | G5798 | [10]-Gingerol ≥98% (HPLC) | 23513-15-7 | 10MG | ₹31327.55 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 42630 | [10]-Gingerol analytical standard | 23513-15-7 | 10MG | ₹55759.58 | 2022-06-14 | Buy |
10-Gingerol Chemical Properties,Uses,Production
Description
10-Gingerol is a phenol that has been found in Z. officinale and has diverse biological activities. It scavenges DPPH , superoxide, and hydroxyl radicals in cell-free assays (IC50s = 10.47, 1.68, and 1.35 μM, respectively) and inhibits oxidative burst induced by N-formyl-Met-Leu-Phe (fMLP; ) in isolated human polymorphonuclear (PMN) neutrophils when used at a concentration of 6 μM. 10-Gingerol inhibits NETosis and the production of reactive oxygen species (ROS) induced by LPS or lupus-relevant stimuli, including ribonucleoprotein-containing immune complexes and anti-phospholipid antibodies, in isolated human neutrophils. It is active against M. avium and M. tuberculosis (MICs = 25 and 50 μg/ml, respectively). 10-Gingerol (200 μM) is also cytotoxic to human MDA-MB-231 and MDA-MB-468 and murine 4T1 and EO771 mammary carcinoma cells.
Uses
(+)-(S)-[10]-Gingerol has been observed to exhibit anti-oxidant behaviour towards lipids and is effective in suppressing obesity and adipose tissue inflammation.
Biochem/physiol Actions
[10]-Gingerol is a bioactive compound found in ginger (Zingiber officinale) with anti-inflammatory and antioxidant activity.
10-Gingerol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29901 | 58 | Inquiry |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | CHINA | 1824 | 58 | Inquiry |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | China | 3424 | 58 | Inquiry |
| Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 | China | 2995 | 58 | Inquiry |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | China | 3000 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-519-519-85557386 | China | 12210 | 58 | Inquiry |
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