HECOGENIN ACETATE
- CAS No.
- 915-35-5
- Chemical Name:
- HECOGENIN ACETATE
- Synonyms
- HECOGENIN ACETATE;HECOGENIN ALCOHOL;HecogeninAcetate>(-)-HECOGENIN ACETATE, TECH., 90%;(25R)-3β-Acetoxy-5α-spirostane-12-one;Hecogenin acetate,()-Hecogenin acetate;(25R)-3β-Acetyloxy-5α-spirostan-12-one;(22R,25R)-3β-Acetoxy-5α-spirostane-12-one;12-oxo-5-alpha-spirostan-3-beta-yl acetate;(25R)-3β-Hydroxy-5α-spirostane-12-one=acetate
- CBNumber:
- CB6442059
- Molecular Formula:
- C29H44O5
- Molecular Weight:
- 472.66
- MOL File:
- 915-35-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/8/26 21:18:56
| Melting point | 246-248 °C (dec.)(lit.) |
|---|---|
| Boiling point | 95-140 °C |
| Density | 1.15±0.1 g/cm3(Predicted) |
| refractive index | -4 ° (C=1, Dioxane) |
| storage temp. | Refrigerator |
| solubility | Chloroform (Sparingly), Dioxane (Sparingly, Heated), Ethyl Acetate (Slightly, Heated) |
| form | Solid |
| color | White |
HECOGENIN ACETATE price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | H4274 | Hecogenin acetate ≥90% | 915-35-5 | 25G | ₹45378.4 | 2022-06-14 | Buy |
| TCI Chemicals (India) | H0537 | Hecogenin Acetate | 915-35-5 | 1G | ₹2700 | 2022-05-26 | Buy |
| TCI Chemicals (India) | H0537 | Hecogenin Acetate | 915-35-5 | 5G | ₹10800 | 2022-05-26 | Buy |
HECOGENIN ACETATE Chemical Properties,Uses,Production
Description
Hecogenin acetate is a steroid sapogenin and an acetylated form of hecogenin that has anthelmintic and antinociceptive properties. It reduces the percentage of mobile larvae in goat fecal cultures containing Haemonchus, Oesophagostomum, and Trichostrongylus nematodes (EC50 = 0.49 mg/ml). Hecogenin acetate (5, 10, or 20 mg/kg, i.p.) inhibits development of mechanical hyperalgesia induced by carrageenan, TNF-α, dopamine , and prostaglandin E2 (PGE2; ) in mice. It also increases latency to tail withdrawal in the tail flick test and has no effect on motor performance in the rotarod test in mice when administered at a dose of 40 mg/kg.
Uses
Hecogenin Acetate, is a derivative of Hecogenin (H129945), which is a sapogenin present in the leaves of species from the Agave genus, possessing wide spectrum of pharmacology activities, such as having antinociceptive properties.
Purification Methods
Crystallise the acetate from MeOH. [Beilstein 19 IV 2583.]
HECOGENIN ACETATE Preparation Products And Raw materials
Raw materials
Preparation Products
HECOGENIN ACETATE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 | China | 3882 | 58 | Inquiry |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | China | 52861 | 58 | Inquiry |
| LEAPCHEM CO., LTD. | +86-852-30606658 | China | 43348 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
| ABCR GmbH & CO. KG | 49 721 95061 0 | Germany | 6846 | 75 | Inquiry |
| Rhawn Reagent | 400-400-1332688 18019345275 | China | 15503 | 58 | Inquiry |
| Rhawn Reagent | 400-1332688 18019345275 | China | 1439 | 58 | Inquiry |
| United States Biological | 800.520.3011 or 781.639.5092 | United States | 6256 | 80 | Inquiry |
| Supplier | Advantage |
|---|---|
| CLEARSYNTH LABS LTD. | 58 |
| TCI Chemicals (India) Pvt. Ltd. | 58 |
| Shaanxi Dideu Medichem Co. Ltd | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 58 |
| LEAPCHEM CO., LTD. | 58 |
| Aladdin Scientific | 58 |
| ABCR GmbH & CO. KG | 75 |
| Rhawn Reagent | 58 |
| Rhawn Reagent | 58 |
| United States Biological | 80 |