SULFISOMIDINE
![SULFISOMIDINE Structure](CAS/GIF/515-64-0.gif)
- CAS No.
- 515-64-0
- Chemical Name:
- SULFISOMIDINE
- Synonyms
- Sulfaisodimidine;SULFISOMIDIN;Domian;erycon;Elcosin;Elkosil;Elkosin;Mefenal;Elcosine;Elkosine
- CBNumber:
- CB6455785
- Molecular Formula:
- C12H14N4O2S
- Molecular Weight:
- 278.33
- MOL File:
- 515-64-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:14
Melting point | 245°C |
---|---|
Boiling point | 294°C (rough estimate) |
Density | 1.2997 (rough estimate) |
refractive index | 1.6440 (estimate) |
storage temp. | 0-6°C |
solubility | Acetonitrile (Slightly), DMSO (Slightly) |
pka | pKa 7.25 (Uncertain) |
form | Solid |
color | White to Off-White |
Water Solubility | 1.382g/L(25 ºC) |
Merck | 8951 |
BRN | 261305 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H315-H319-H335 |
Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 22-24/25-36-26 |
RIDADR | 3249 |
WGK Germany | 2 |
RTECS | WO9270000 |
HazardClass | 6.1(b) |
PackingGroup | III |
SULFISOMIDINE Chemical Properties,Uses,Production
Uses
Sulfisomidine is a sulfanilamide antibacterial agent.
Definition
ChEBI: A sulfonamide consisting of pyrimidine having methyl substituents at the 2- and 6-positions and a 4-aminobenzenesulfonamido group at the 4-position.
World Health Organization (WHO)
Sulfisomide, a sulfonamide anti-infective agent, was introduced several decades ago for the treatment of bacterial infections. The importance of sulfonamides has subsequently decreased as a result of increasing resistance and their replacement by antibiotics which are generally more active and less toxic. The sulfonamides are known to cause serious adverse effects such as renal toxicity, sometimes fatal exfoliative dermatitis and erythema multiforma and dangerous adverse reactions affecting blood formation such as agranulocytosis and haemolytic or aplastic anaemia. Sulfisomide is still used topically in some countries for vaginal infection.
Pharmaceutical Applications
6-Sulfanilamido-2,4-dimethylpyrimidine (syn: sulphasomidine). A highly soluble sulfonamide with a plasma half-life of 6–8 h. Protein binding is about 90%. Activity is similar to that of sulfadiazine. It is less extensively metabolized than most other sulfonamides and is largely excreted unchanged in the urine.
SULFISOMIDINE Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29897 | 58 | Inquiry |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | China | 34571 | 58 | Inquiry |
WinWin Chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | China | 14200 | 58 | Inquiry |
Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | China | 52861 | 58 | Inquiry |
Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 | China | 9003 | 58 | Inquiry |
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