L-745,870 TRIHYDROCHLORIDE

L-745,870 TRIHYDROCHLORIDE Structure
CAS No.
158985-00-3
Chemical Name:
L-745,870 TRIHYDROCHLORIDE
Synonyms
3HCl;L 745870;L 745870,L745870;L-745,870 trihydroch;L-745,870 TRIHYDROCHLORIDE;3-[[4-(4-Chlorophenyl)-1-piperazinyl]methyl]-1H-pyrrolo[2,3-b]pyridine;1H-Pyrrolo[2,3-b]pyridine, 3-[[4-(4-chlorophenyl)-1-piperazinyl]methyl]-;3-(4-[4-CHLOROPHENYL]PIPERAZIN-1-YL)-METHYL-1H-PYRROLO[2,3-B]PYRIDINE TRIHYDROCHLORIDE
CBNumber:
CB6481216
Molecular Formula:
C18H19ClN4
Molecular Weight:
326.82
MOL File:
158985-00-3.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:14

L-745,870 TRIHYDROCHLORIDE Properties

Boiling point 571.4±50.0 °C(Predicted)
Density 1.31±0.1 g/cm3(Predicted)
storage temp. Desiccate at +4°C
solubility DMSO:16.5(Max Conc. mg/mL);50.49(Max Conc. mM)
pka 8.20±0.20(Predicted)
form Solid
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

L-745,870 TRIHYDROCHLORIDE Chemical Properties,Uses,Production

Biological Activity

A highly potent and selective D 4 dopamine receptor antagonist; L-745,870 has K i values of 0.51, 2300 and 960 nM for D 4 , D 3 and D 2 subtypes respectively and > 1000-fold selectivity over 5-HT 2 , D 1 and D 5 receptors.

L-745,870 TRIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 38)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 China 49739 58 Inquiry
Zibo Hangyu Biotechnology Development Co., Ltd +86-0533-2185556 +8617865335152 China 11027 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43348 58 Inquiry
Beijing Stronger Science Co., Ltd. 0531-88924771 15614660963 China 10624 58 Inquiry
RD International Technology Co., Limited 18024082417 China 9155 58 Inquiry
Bide Pharmatech Ltd. 400-1647117 15221909166 China 63720 58 Inquiry
Henan Alpha Chemical Co., Ltd. 0371-55013243 15324716602 China 10015 58 Inquiry
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 China 3717 55 Inquiry
L-745,870 TRIHYDROCHLORIDE 3HCl 3-(4-[4-CHLOROPHENYL]PIPERAZIN-1-YL)-METHYL-1H-PYRROLO[2,3-B]PYRIDINE TRIHYDROCHLORIDE L 745870 3-[[4-(4-Chlorophenyl)-1-piperazinyl]methyl]-1H-pyrrolo[2,3-b]pyridine 1H-Pyrrolo[2,3-b]pyridine, 3-[[4-(4-chlorophenyl)-1-piperazinyl]methyl]- L-745,870 trihydroch L 745870,L745870 158985-00-3 C18H22Cl4N4 C18H19N4Cl3HCl