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Bosentan hydrate

Bosentan hydrate Structure
CAS No.
157212-55-0
Chemical Name:
Bosentan hydrate
Synonyms
CS-170;Bosetan;bosentan hydrate;Bosentan (200 mg);Bosentan (1076115);Bosentan monohydrate;Bosentan hydrate USP/EP/BP;Bosentan Hydrate See B675900;Bosentan Hydrate (Ro 47-0203);Tracleer, Bosentan monohydrate
CBNumber:
CB6547457
Molecular Formula:
C27H31N5O7S
Molecular Weight:
569.62934
MOL File:
157212-55-0.mol
MSDS File:
SDS
Modify Date:
2023/5/18 11:31:00

Bosentan hydrate Properties

Melting point 114-118 °C
storage temp. 2-8°C
solubility DMSO (Slightly), Methanol (Very Slightly, Heated)
form powder
color white to beige
Merck 14,1353

SAFETY

Risk and Safety Statements

Hazard statements  H412
Precautionary statements  P273
HS Code  2935909550

Bosentan hydrate price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) SML1265 Bosentan hydrate ≥98% (HPLC) 157212-55-0 10MG ₹10716.75 2022-06-14 Buy
Sigma-Aldrich(India) SML1265 Bosentan hydrate ≥98% (HPLC) 157212-55-0 50MG ₹43613.93 2022-06-14 Buy
Sigma-Aldrich(India) PHR2708 Bosentan certified reference material, pharmaceutical secondary standard 157212-55-0 500MG ₹34066.28 2022-06-14 Buy
TCI Chemicals (India) B5118 Bosentan Monohydrate 157212-55-0 25MG ₹2800 2022-05-26 Buy
TCI Chemicals (India) B5118 Bosentan Monohydrate 157212-55-0 100MG ₹9500 2022-05-26 Buy
Product number Packaging Price Buy
SML1265 10MG ₹10716.75 Buy
SML1265 50MG ₹43613.93 Buy
PHR2708 500MG ₹34066.28 Buy
B5118 25MG ₹2800 Buy
B5118 100MG ₹9500 Buy

Bosentan hydrate Chemical Properties,Uses,Production

Uses

Bosentan hydrate has been used in cell viability assay. It has also been used as a positive control for calcium transient analysis.

brand name

Tracleer (Actelion).

Biochem/physiol Actions

Bosentan is an endothelin receptor antagonist. Endothelin is a potent vasoconstrictor, making antagonists of clinical interest for the treatment of conditions associated with vasospasm, such as subarachnoid hemorrhage (SAH) and hypertension. Bosentan is a dual endothelin receptor antagonist effective in the treatment of pulmonary arterial hypertension (PAH), the first of the class to make it to market. Bosentan is an orally available, competitive antagonist of both the ETA and ETB receptor subtypes with a Ki of 4.7 nM for ETA and a Ki of 95 nM for ETB.

Bosentan hydrate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 358)Suppliers
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Bosentan hydrate Spectrum

Bosetan 4-(tert-Butyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfona 4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-Methoxyphenoxy)-2-(pyriMidin-2-yl)pyriMidin-4-yl]benzene-1-sulfonaMide Bosentan Hydrate See B675900 Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-, hydrate (1:1) Bosentan (200 mg) bosentan hydrate Bosentan monohydrate 4-(1,1-dimethylethyl)-n-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)(2,2'-bipyrimidin)-4-yl)benzenesulfonamide monohydrate CS-170 4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-(pyrimidin-2-yl)pyrimidin-4-yl]benzene-1-sulfonamide hydrate Bosentan hydrate USP/EP/BP Bosentan Hydrate (Ro 47-0203) 4-(tert-Butyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide hydrate[Ro-47-0203 Hydrate Bosentan MonohydrateQ: What is Bosentan Monohydrate Q: What is the CAS Number of Bosentan Monohydrate Q: What is the storage condition of Bosentan Monohydrate Q: What are the applications of Bosentan Monohydrate Bosentan HydrateQ: What is Bosentan Hydrate Q: What is the CAS Number of Bosentan Hydrate Q: What is the storage condition of Bosentan Hydrate Q: What are the applications of Bosentan Hydrate Bosentan (1076115) Tracleer, Bosentan monohydrate Bosentan Monohydrate/Bosentan Hydrate 4-(tert-Butyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide hydrate 157212-55-0 C27H29N5O6SH2O 9N5O6SH2O C27H31N5O7S C27H29N5O6S2O Inhibitors API Heterocyclic Compounds