2-FLUORO-3-OXO-3-PHENYLPROPIONIC ACID ETHYL ESTER

2-FLUORO-3-OXO-3-PHENYLPROPIONIC ACID ETHYL ESTER Structure
CAS No.
1479-22-7
Chemical Name:
2-FLUORO-3-OXO-3-PHENYLPROPIONIC ACID ETHYL ESTER
Synonyms
Ethyl 2-fluoro-3-oxo-3-phenylpropanoate;2-FLUORO-3-OXO-3-PHENYLPROPIONIC ACID ETHYL ESTER;Benzenepropanoic acid, α-fluoro-β-oxo-, ethyl ester;Benzenepropanoic acid, α-fluoro-β-oxo-, ethyl ester;R,S-2-Fluoro-3-oxo-3-phenyl-propionicacidethylester;(R,S)-2-Fluoro-3-oxo-3-phenyl-propionicacidethylester
CBNumber:
CB6744898
Molecular Formula:
C11H11FO3
Molecular Weight:
210.2
MOL File:
1479-22-7.mol
Modify Date:
2023/5/4 15:12:49

2-FLUORO-3-OXO-3-PHENYLPROPIONIC ACID ETHYL ESTER Properties

Melting point 33-35 °C
Boiling point 116°C 0,3mm
Density 1.169±0.06 g/cm3(Predicted)
pka 8.20±0.26(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H335-H319
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
Risk Statements  36/37/38
Safety Statements  26-36/37/39

2-FLUORO-3-OXO-3-PHENYLPROPIONIC ACID ETHYL ESTER Chemical Properties,Uses,Production

Uses

Ethyl 2-Benzoyl-2-fluoroacetate is used in the chemoselective preparation of α-chloro- and α-fluoro-β-keto esters by chlorination or fluorination with N-chlorosuccinimide or Selectfluor in the presence of titanium catalysts such as (cyclopentadienyl)titanium trichloride.

Synthesis Reference(s)

The Journal of Organic Chemistry, 56, p. 273, 1991 DOI: 10.1021/jo00001a052
Tetrahedron Letters, 37, p. 653, 1996 DOI: 10.1016/0040-4039(95)02224-4

2-FLUORO-3-OXO-3-PHENYLPROPIONIC ACID ETHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

2-FLUORO-3-OXO-3-PHENYLPROPIONIC ACID ETHYL ESTER Suppliers

Global( 11)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
ABCR GmbH & CO. KG 49 721 95061 0 Germany 6846 75 Inquiry
Jiangsu aikang biomedical research and development co., LTD 025-66110311 13155353615 China 15527 58 Inquiry
Interchim S.A. (33) 4 70 03 88 55 France 6307 76 Inquiry
3B Scientific Corporation 847.281.9822 United States 6744 47 Inquiry
Shanghai Qiao Chemical Science Co., Ltd 021-58892003 China 5906 65 Inquiry
TCI (Shanghai) Chemical Trading Co., Ltd. 021-021-61109150 China 31163 58 Inquiry
JinJin Le Chemical Co., Ltd 10106090 China 9981 58 Inquiry
Shaanxi Dideu Medichem Co. Ltd 029-81124267 15229202216 China 9998 58 Inquiry
Shanghai Haohong Pharmaceutical Co., Ltd. 4008210725 4008210725 China 54986 58 Inquiry
(R,S)-2-Fluoro-3-oxo-3-phenyl-propionicacidethylester R,S-2-Fluoro-3-oxo-3-phenyl-propionicacidethylester 2-FLUORO-3-OXO-3-PHENYLPROPIONIC ACID ETHYL ESTER Ethyl 2-fluoro-3-oxo-3-phenylpropanoate Benzenepropanoic acid, α-fluoro-β-oxo-, ethyl ester Benzenepropanoic acid, α-fluoro-β-oxo-, ethyl ester 1479-22-7