Butyrylcholinesterase
- CAS No.
- 9001-08-5
- Chemical Name:
- Butyrylcholinesterase
- Synonyms
- Protexia;BtChoEase;EC 3.1.1.8;EC: 3.1.1.8;IUB: 3.1.1.8;E.C. 3.1.1.9;CHOLINESTERASE;choline esterase;Cholinesterase II;Choline esterase II
- CBNumber:
- CB6778613
- Molecular Formula:
- Molecular Weight:
- 0
- MOL File:
- Mol file
- MSDS File:
- SDS
- Modify Date:
- 2023/6/30 17:01:55
| Melting point | 177-178.1 °C(Solv: ligroine (8032-32-4)) |
|---|---|
| storage temp. | -20°C |
| form | powder |
| color | light brown |
| Merck | 13,2229 |
| EPA Substance Registry System | Esterase, choline (9001-08-5) |
Butyrylcholinesterase price More Price(2)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | C1057 | Butyrylcholinesterase from equine serum lyophilized powder, ≥900?units/mg protein | 9001-08-5 | 1000UNITS | ₹43123.5 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | C1057 | Butyrylcholinesterase from equine serum lyophilized powder, ≥900?units/mg protein | 9001-08-5 | 5000UNITS | ₹172183.2 | 2022-06-14 | Buy |
Butyrylcholinesterase Chemical Properties,Uses,Production
Uses
Selective inhibition of BChE activity, Butyrylcholinesterase can be used in the detection of organophosphates.Its use in the treatment of organophosphate toxicity has been explored. It has been reported that the level of BChE in human blood correlates to the degree of protection against potentially toxic nerve agents.Cholinesterases have also been investigated for their role in Alzheimer’s disease.
Biological Functions
Butyrylcholinesterase (BuChE) is found in plasma, the liver, and the kidney. Its activity is also inhibited by carbamate insecticides. BuChE is able to hydrolyze much larger substrates than AChE due to differences in their structure that allow BuChE to bind bulky ligands. The physiological role of BuChE is not completely understood, but it represents an important detoxification pathway for anticholinesterase compounds (Sultatos, 2006).
General Description
Butyrylcholinesterase (BChE) is a serine hydrolase that is structurally similar to acetylcholinesterase (AChE), but differs in substrate specificities and inhibitor sensitivities. The enzyme is a tetrameric glycoprotein with four equal subunits (110 kDa each). It is also termed as pseudocholinesterase. It is produced in the liver. It is found in blood, the synapse of neuromuscular junctions and glia cells and axons of white matter.
Butyrylcholinesterase Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Hangzhou ICH Biofarm Co., Ltd | +86-0571-28186870; +undefined8613073685410 | China | 985 | 58 | Inquiry |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 25196 | 58 | Inquiry |
| Henan Alfa Chemical Co., Ltd | +8618339805032 | China | 13140 | 58 | Inquiry |
| LEAPCHEM CO., LTD. | +86-852-30606658 | China | 43348 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
| Wuhan Fortuna Chemical Co.,Ltd | +8618007136271 | China | 5639 | 58 | Inquiry |
| Hubei wei shi reagent group ltd., company | 027-59102966 18627096350 | China | 2828 | 58 | Inquiry |
| Lingyuan Bebiansen Biological Technology Co., Ltd | 18642120371 | China | 7994 | 58 | Inquiry |
| Shanghai Harmony Bio-Pharmaceutical Technology Co., Ltd. | 021-18019086215 18019086215 | China | 790 | 58 | Inquiry |
| Shandong Xiya Chemical Co., Ltd. | 4009903999 13395398332 | China | 20810 | 60 | Inquiry |
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