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L-759,633

L-759,633 Structure
CAS No.
174627-50-0
Chemical Name:
L-759,633
Synonyms
L-759;L 759;L-759,633;L759633,L-759633;(6aR,10aR)-1-methoxy-6,6,9-trimethyl-3-(2-methyloctan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromene;(6aR,10aR)-3-(1,1-Dimethylheptyl)-6a,7,10,10a-tetrahydro-1-methoxy-6,6,9-trimethyl-6H-dibenzo[b,d]pyran;6H-Dibenzo[b,d]pyran, 3-(1,1-dimethylheptyl)-6a,7,10,10a-tetrahydro-1-methoxy-6,6,9-trimethyl-, (6aR,10aR)-
CBNumber:
CB6837204
Molecular Formula:
C26H40O2
Molecular Weight:
384.59
MOL File:
174627-50-0.mol
Modify Date:
2023/6/8 9:03:08
Request For Quotation

L-759,633 Properties

Boiling point 447.9±45.0 °C(Predicted)
Density 0.956±0.06 g/cm3(Predicted)
storage temp. Store at +4°C
solubility Ethanol:20.0(Max Conc. mg/mL);52.0(Max Conc. mM)
PBS (pH 7.2):0.25(Max Conc. mg/mL);0.65(Max Conc. mM)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319-H336
Precautionary statements  P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501
NFPA 704
3
2 0

L-759,633 Chemical Properties,Uses,Production

Description

L-759,633 is a high-affinity peripheral cannabinoid receptor (CB2)-selective agonist with Ki values of 6.4 and 1,043 nM for CB2 and central cannabinoid (CB1) receptors, respectively. L-759,633 inhibits forskolin-stimulated cyclic AMP production in CHO cells transfected with CB2 or CB1 receptors with IC50 values of 8.1 nM and 10 μM, respectively.

Biological Activity

High affinity, selective CB 2 receptor agonist (K i values are 6.4 and 1043 nM for CB 2 and CB 1 receptors respectively). Potently inhibits forskolin-stimulated cAMP production via CB 2 receptors expressed in CHO cells (EC 50 = 8.1 nM).

L-759,633 Preparation Products And Raw materials

Raw materials

Preparation Products

L-759,633 Suppliers

Global( 27)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 China 11975 58 Inquiry
Cayman Chemical Company (800) 364-9897 United States 6618 81 Inquiry
Wako Pure Chemical Industries, Ltd. +81 6 6203 3741 Japan 6828 80 Inquiry
AXXORA, LLC +41 (0) 61 926 8989 Switzerland 1104 80 Inquiry
Service Chemical Inc. 888-895-6920 Germany 6373 71 Inquiry
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 China 15848 69 Inquiry
Tocris Bioscience +44 (0) 117 916 3333 United Kingdom 5729 77 Inquiry
United States Biological 1-800-520-3011 United States 6106 58 Inquiry
Supplier Advantage
TargetMol Chemicals Inc. 58
Aladdin Scientific 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
Cayman Chemical Company 81
Wako Pure Chemical Industries, Ltd. 80
AXXORA, LLC 80
Service Chemical Inc. 71
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Tocris Bioscience 77
United States Biological 58

174627-50-0(L-759,633)Related Search:

DELTA-8-THC L-759,633 5-(1,1-DIMETHYL-HEPTYL)RESORCINOL 4-(2-ETHOXYPHENYL)-2-METHYL-1-BUTENE 1-(1 1-DIMETHYLHEPTYL)-3 5-DIMETHOXYBEN&
ethyl-delta-8-tetrahydrocannabinol (6AR,10AR)-3-(1,1-DIMETHYLBUTYL)-6A,7,10,10A-TETRAHYDRO-6,6,9-TRIMETHYL-6H-DIBENZO[B,D]PYRAN
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L-759,633 (6aR,10aR)-3-(1,1-Dimethylheptyl)-6a,7,10,10a-tetrahydro-1-methoxy-6,6,9-trimethyl-6H-dibenzo[b,d]pyran (6aR,10aR)-1-methoxy-6,6,9-trimethyl-3-(2-methyloctan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromene 6H-Dibenzo[b,d]pyran, 3-(1,1-dimethylheptyl)-6a,7,10,10a-tetrahydro-1-methoxy-6,6,9-trimethyl-, (6aR,10aR)- L 759 L-759 L759633,L-759633 174627-50-0 C26H40O2 Cannabinoid receptor