N-(3R)-1-AZABICYCLO[2.2.2]OCT-3-YL-4-CHLOROBENZAMIDE
![N-(3R)-1-AZABICYCLO[2.2.2]OCT-3-YL-4-CHLOROBENZAMIDE Structure](CAS/GIF/123464-89-1.gif)
- CAS No.
- 123464-89-1
- Chemical Name:
- N-(3R)-1-AZABICYCLO[2.2.2]OCT-3-YL-4-CHLOROBENZAMIDE
- Synonyms
- SKL843;CS-1012;PNU 282987;PNU282987 HCl;Lanreotide Autogel;PNU 282987(PNU 282987 hydrochloride);PNU 282987 - CAS 123464-89-1 - Calbiochem;N-(3R)-1-AZABICYCLO[2.2.2]OCT-3-YL-4-CHLOROBENZAMIDE;(R)-4-Chloro-N-(quinuclidin-3-yl)benzamide hydrochloride;N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-4-chlorobenzamide hydrochloride
- CBNumber:
- CB6847535
- Molecular Formula:
- C14H17ClN2O
- Molecular Weight:
- 264.75058
- MOL File:
- 123464-89-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/9/20 16:43:00
Melting point | 240-242℃ |
---|---|
storage temp. | Inert atmosphere,2-8°C |
solubility | Soluble in DMSO (up to 25 mg/ml) |
form | Off-white solid |
color | White |
Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months. |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H315-H319-H335 |
Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a |
N-(3R)-1-AZABICYCLO[2.2.2]OCT-3-YL-4-CHLOROBENZAMIDE Chemical Properties,Uses,Production
Uses
PNU 282987 is used as an activator of α-7 nicotinic acetylcholine receptor.
General Description
A potent agonist highly selective for α7 nAChRs (Ki = 26 nM). Used in investigating the roles of α7 nAChRs in sensory gating, learning and memory, cognitive functions, and treatment of Schizophrenia.
Biological Activity
Highly selective α 7 nAChR agonist (K i = 26 nM) displaying negligible blockade of α 1 β 1 γ δ and α 3 β 4 nAChRs (IC 50 ≥ 60 μ M). Found to be inactive against a panel of 32 receptors at 1 μ M, except 5-HT 3 receptors (K i = 930 nM).
N-(3R)-1-AZABICYCLO[2.2.2]OCT-3-YL-4-CHLOROBENZAMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 118)Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32836 | 60 | Inquiry |
BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29825 | 58 | Inquiry |
SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | China | 5738 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | China | 10522 | 58 | Inquiry |
InvivoChem | +1-708-310-1919 +1-13798911105 | United States | 6393 | 58 | Inquiry |
LEAP CHEM CO., LTD. | +86-852-30606658 | China | 24738 | 58 | Inquiry |
123464-89-1(N-(3R)-1-AZABICYCLO[2.2.2]OCT-3-YL-4-CHLOROBENZAMIDE)Related Search:
Tamoxifen citrate
REVERSINE
(E)-3-[[[3-[2-(7-CHLORO-2-QUINOLINYL)ETHENYL]PHENYL]-[[(3-DIMETHYLAMINO)-3-OXOPROPYL]THIO]METHYL]THIO]-PROPANOIC ACID, SODIUM SALT
THIP HYDROCHLORIDE
PNU-282987 S enantiomer hydrochloride
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N-(3R)-1-AZABICYCLO[2.2.2]OCT-3-YL-4-CHLOROBENZAMIDE
PNU 282987
N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-4-chlorobenzamide hydrochloride
N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-4-chlorobenzamide hydrochloride PNU 282987
PNU282987 HCl
PNU 282987(PNU 282987 hydrochloride)
CS-1012
PNU 282987 - CAS 123464-89-1 - Calbiochem
SKL843
Lanreotide Autogel
(R)-4-Chloro-N-(quinuclidin-3-yl)benzamide hydrochloride
123464-89-1
C14H17ClN2OHCl
Inhibitors
Acetylcholine receptor