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TYLOPHORIDICINE A(), 98+%

TYLOPHORIDICINE A(), 98+% Structure
CAS No.
32523-69-6
Chemical Name:
TYLOPHORIDICINE A(), 98+%
Synonyms
Tylophorinidine;TYLOPHORIDICINE A(), 98+%;(13aS,14S)-3,7-dimethoxy-9,11,12,13,13a,14-hexahydrophenanthro[10,9-f]indolizine-6,14-diol;(13aS,14S)-9,11,12,13,13a,14-Hexahydro-3,7-dimethoxydibenzo[f,h]pyrrolo[1,2-b]isoquinoline-6,14-diol;(12aS,13S)-3,7-Dimethoxy-6,13-dihydroxy-9,10,11,12,12a,13-hexahydro-9a-aza-9aH-cyclopenta[b]triphenylene;Dibenzo[f,h]pyrrolo[1,2-b]isoquinoline-6,14-diol, 9,11,12,13,13a,14-hexahydro-3,7-dimethoxy-, (13aS,14S)-
CBNumber:
CB6992493
Molecular Formula:
C22H23NO4
Molecular Weight:
365.42
MOL File:
32523-69-6.mol
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TYLOPHORIDICINE A(), 98+% Properties

Melting point 2l3-4°C(dec.).
Boiling point 613.5±55.0 °C(Predicted)
Density 1.38±0.1 g/cm3(Predicted)
pka 9.66±0.40(Predicted)

TYLOPHORIDICINE A(), 98+% Chemical Properties,Uses,Production

Description

The most recently discovered of the Tylophora alkaloids, this base is found in the roots of T. asthmatica and has [α]25D + 108° (c 1.91, MeOH). The ultraviolet spectrum in MeOH has absorption maxima at 258, 286.5, 310, 339.5 and 355 Mu. Two methoxyl groups and two phenolic hydroxyl groups are present and the alkaloid furnishes the O,O-dimethyl ether, m.p. 2l8-2200 C (dec.) and the diacetate, m.p. 192°C.

Uses

Tylophorinidine is used in biological studies for thymidylate synthase in leukocytes from patients with chronic myelocytic leukemia and acute lymphocytic leukemia. It allows for inhibition of pergularinine and tylophorinidine (Erratum).

References

Mulchandani, Iyer, Badheka., Chem. Ind., 505 (1971)

TYLOPHORIDICINE A(), 98+% Preparation Products And Raw materials

Raw materials

Preparation Products

TYLOPHORIDICINE A(), 98+% Suppliers

Global( 7)Suppliers
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CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Chengdu Push Bio-Technology Co., Ltd. 18080489829 China 9209 58 Inquiry
TargetMol Chemicals Inc. 15002134094 China 28091 58 Inquiry
CHEMICAL LAND21 82- 2 -783 - 8063 South Korea 6315 74 Inquiry
Lanospharma Laboratories Co.,Ltd 13440048448 China 6343 56 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
Chengdu Push Bio-Technology Co., Ltd. 58
TargetMol Chemicals Inc. 58
CHEMICAL LAND21 74
Lanospharma Laboratories Co.,Ltd 56

32523-69-6(TYLOPHORIDICINE A(), 98+%)Related Search:

Triphenylene
Tylophorinidine TYLOPHORIDICINE A(), 98+% (12aS,13S)-3,7-Dimethoxy-6,13-dihydroxy-9,10,11,12,12a,13-hexahydro-9a-aza-9aH-cyclopenta[b]triphenylene (13aS,14S)-9,11,12,13,13a,14-Hexahydro-3,7-dimethoxydibenzo[f,h]pyrrolo[1,2-b]isoquinoline-6,14-diol (13aS,14S)-3,7-dimethoxy-9,11,12,13,13a,14-hexahydrophenanthro[10,9-f]indolizine-6,14-diol Dibenzo[f,h]pyrrolo[1,2-b]isoquinoline-6,14-diol, 9,11,12,13,13a,14-hexahydro-3,7-dimethoxy-, (13aS,14S)- 32523-69-6