trans-(-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamidehydrochloride

CAS No.: 67198-13-4

Chemical Name:: trans-(-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamidehydrochloride

Synonyms: u59900;U50,488;(+/-)-trans-U-50488;(+/-)-U-50488 hydroc;U-50488 mesylate (±)-;Top supplier U58800 U-50488 CAS NO.67198-13-4;2-(3,4-dichlorophenyl)-N-methyl-N-(2-pyrrolidin-1-ylcyclohexyl)acetami de;N-Methyl-N-[2α-(1-pyrrolidinyl)cyclohexan-1β-yl]-3,4-dichlorophenylacetamide;N-Methyl-N-[(1β,2α)-2-(1-pyrrolidinyl)cyclohexyl]-3,4-dichlorophenylacetamide;3,4-Dichloro-N-methyl-N-[2α-(pyrrolidin-1-yl)cyclohexan-1β-yl]benzeneacetamide

CBNumber:: CB71075363

Molecular Formula:: C19H26Cl2N2O

Molecular Weight:: 369.33

MOL File:: 67198-13-4.mol

Modify Date:: 2022/12/21 16:56:50

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trans-(-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamidehydrochloride Properties

Melting point	204-208℃
RTECS	CY1484710
storage temp.	Desiccate at RT

trans-(-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamidehydrochloride Chemical Properties,Uses,Production

Uses

U 50488 is a selective κ-opioid agonist with analgesic, diuretic, and antitussive properties. κ-opioid agonists are useful compounds to elucidate the functions of κ-receptors in the central nervous system.

Definition

ChEBI: A monocarboxylic acid amide obtained by formal condensation between the carboxy group of 3,4-dichlorophenylacetic acid and the secondary amino group of (1R,2R)-N-methyl-2-(pyrrolidin-1-yl)cyclohexanamine

Biological Activity

Selective κ -opioid agonist. At higher concentrations blocks Na + channels. See separate isomers (trans-(-)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide hydrochloride and 0471 ).

trans-(-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamidehydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

trans-(-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamidehydrochloride Suppliers

Global( 10)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	China	15848	69	Inquiry
Shanghai Synchem Pharma Co., ltd	21-619849051-1 18521059765	China	6457	55	Inquiry
Service Chemical Inc.	888-895-6920	Germany	6373	71	Inquiry
HONEST JOY HOLDINGS LIMITED	+86-755-26404303	United States	6702	54	Inquiry
Tocris Bioscience	+44 (0) 117 916 3333	United Kingdom	5729	77	Inquiry
United States Biological	1-800-520-3011	United States	6106	58	Inquiry
United States Biological	800.520.3011 or 781.639.5092	United States	6256	80	Inquiry
Shanghai Universal Biotech Co.,Ltd	18768175414	China	24998	58	Inquiry

Supplier	Advantage
3B Pharmachem (Wuhan) International Co.,Ltd.	69
Shanghai Synchem Pharma Co., ltd	55
Service Chemical Inc.	71
HONEST JOY HOLDINGS LIMITED	54
Tocris Bioscience	77
United States Biological	58
United States Biological	80
Shanghai Universal Biotech Co.,Ltd	58

67198-13-4(trans-(-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamidehydrochloride)Related Search:

(+)-U-50488 HYDROCHLORIDE trans-(-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamidehydrochloride (-)-(1S,2R)-CIS-3,4-DICHLORO-N-METHYL-N-[2-(1-PYRROLIDINYL)-CYCLOHEXYL]-BENZENEACETAMIDE TARTRATE (+/-)-(5ALPHA,7ALPHA,8BETA)-3,4-DICHLORO-N-METHYL-N-(7-[1-PYRROLIDINYL]-1-OXASPIRO[4.5]DEC-8-YL)BENZENEACETAMIDE MESYLATE

N-Methyl-N-[2α-(1-pyrrolidinyl)cyclohexan-1β-yl]-3,4-dichlorophenylacetamide (+/-)-trans-U-50488 U50,488 2-(3,4-dichlorophenyl)-N-methyl-N-(2-pyrrolidin-1-ylcyclohexyl)acetami de trans-(±)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide mesylate rel-3,4-Dichloro-N-methyl-N-[(1α*)-2β*-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide 3,4-Dichloro-N-methyl-N-[(1β,2α)-2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide 3,4-Dichloro-N-methyl-N-[2α-(pyrrolidin-1-yl)cyclohexan-1β-yl]benzeneacetamide N-Methyl-N-[(1β,2α)-2-(1-pyrrolidinyl)cyclohexyl]-3,4-dichlorophenylacetamide 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer U-50488 mesylate (±)- 2-(3,4-dichlorophenyl)-N-methyl-N-[(1R,2R)-2-pyrrolidin-1-ylcyclohexyl]acetamide u59900 Top supplier U58800 U-50488 CAS NO.67198-13-4 Benzeneacetamide, 3,4-dichloro-N-methyl-N-[(1R,2R)-2-(1-pyrrolidinyl)cyclohexyl]-, rel- (+/-)-U-50488 hydroc 67198-13-4 C19H26Cl2N2O Opioid receptor and opioid-like receptor