trans-(-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamidehydrochloride
![trans-(-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamidehydrochloride Structure](CAS/GIF/67198-13-4.gif)
- CAS No.
- 67198-13-4
- Chemical Name:
- trans-(-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamidehydrochloride
- Synonyms
- u59900;U50,488;(+/-)-trans-U-50488;(+/-)-U-50488 hydroc;U-50488 mesylate (±)-;Top supplier U58800 U-50488 CAS NO.67198-13-4;2-(3,4-dichlorophenyl)-N-methyl-N-(2-pyrrolidin-1-ylcyclohexyl)acetami de;N-Methyl-N-[2α-(1-pyrrolidinyl)cyclohexan-1β-yl]-3,4-dichlorophenylacetamide;N-Methyl-N-[(1β,2α)-2-(1-pyrrolidinyl)cyclohexyl]-3,4-dichlorophenylacetamide;3,4-Dichloro-N-methyl-N-[2α-(pyrrolidin-1-yl)cyclohexan-1β-yl]benzeneacetamide
- CBNumber:
- CB71075363
- Molecular Formula:
- C19H26Cl2N2O
- Molecular Weight:
- 369.33
- MOL File:
- 67198-13-4.mol
- Modify Date:
- 2022/12/21 16:56:50
trans-(-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamidehydrochloride Chemical Properties,Uses,Production
Uses
U 50488 is a selective κ-opioid agonist with analgesic, diuretic, and antitussive properties. κ-opioid agonists are useful compounds to elucidate the functions of κ-receptors in the central nervous system.
Definition
ChEBI: A monocarboxylic acid amide obtained by formal condensation between the carboxy group of 3,4-dichlorophenylacetic acid and the secondary amino group of (1R,2R)-N-methyl-2-(pyrrolidin-1-yl)cyclohexanamine
Biological Activity
Selective κ -opioid agonist. At higher concentrations blocks Na + channels. See separate isomers (trans-(-)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide hydrochloride and 0471 ).
trans-(-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamidehydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 10)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| 821-50328103-801 18930552037 | China | 15839 | 69 | Inquiry | |
| Shanghai Synchem Pharma Co., ltd | 21-619849051-1 18521059765 | China | 6466 | 55 | Inquiry |
| Service Chemical Inc. | 888-895-6920 | Germany | 6350 | 71 | Inquiry |
| HONEST JOY HOLDINGS LIMITED | +86-755-26404303 | United States | 6675 | 54 | Inquiry |
| Tocris Bioscience | +44 (0) 117 916 3333 | United Kingdom | 5726 | 77 | Inquiry |
| United States Biological | 1-800-520-3011 | United States | 6075 | 58 | Inquiry |
| United States Biological | 800.520.3011 or 781.639.5092 | United States | 6214 | 80 | Inquiry |
| Shanghai Universal Biotech Co.,Ltd | 13774214275 | China | 25002 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| 69 | |
| Shanghai Synchem Pharma Co., ltd | 55 |
| Service Chemical Inc. | 71 |
| HONEST JOY HOLDINGS LIMITED | 54 |
| Tocris Bioscience | 77 |
| United States Biological | 58 |
| United States Biological | 80 |
| Shanghai Universal Biotech Co.,Ltd | 58 |
67198-13-4(trans-(-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamidehydrochloride)Related Search:
(+)-U-50488 HYDROCHLORIDE
trans-(-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamidehydrochloride
(-)-(1S,2R)-CIS-3,4-DICHLORO-N-METHYL-N-[2-(1-PYRROLIDINYL)-CYCLOHEXYL]-BENZENEACETAMIDE TARTRATE
(+/-)-(5ALPHA,7ALPHA,8BETA)-3,4-DICHLORO-N-METHYL-N-(7-[1-PYRROLIDINYL]-1-OXASPIRO[4.5]DEC-8-YL)BENZENEACETAMIDE MESYLATE
N-Methyl-N-[2α-(1-pyrrolidinyl)cyclohexan-1β-yl]-3,4-dichlorophenylacetamide
(+/-)-trans-U-50488
U50,488
2-(3,4-dichlorophenyl)-N-methyl-N-(2-pyrrolidin-1-ylcyclohexyl)acetami de
trans-(±)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide mesylate
rel-3,4-Dichloro-N-methyl-N-[(1α*)-2β*-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide
3,4-Dichloro-N-methyl-N-[(1β,2α)-2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide
3,4-Dichloro-N-methyl-N-[2α-(pyrrolidin-1-yl)cyclohexan-1β-yl]benzeneacetamide
N-Methyl-N-[(1β,2α)-2-(1-pyrrolidinyl)cyclohexyl]-3,4-dichlorophenylacetamide
3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer
U-50488 mesylate (±)-
2-(3,4-dichlorophenyl)-N-methyl-N-[(1R,2R)-2-pyrrolidin-1-ylcyclohexyl]acetamide
u59900
Top supplier U58800 U-50488 CAS NO.67198-13-4
Benzeneacetamide, 3,4-dichloro-N-methyl-N-[(1R,2R)-2-(1-pyrrolidinyl)cyclohexyl]-, rel-
(+/-)-U-50488 hydroc
67198-13-4
C19H26Cl2N2O
Opioid receptor and opioid-like receptor