Acronine

Acronine Structure
CAS No.
7008-42-6
Chemical Name:
Acronine
Synonyms
Acronine;NSC-403169;NCI-C 01536;Compound 42339;Acronycine (Acronine);3,12-Dihydro-6-methoxy-3,3,12-trimethyl-7H-pyrano[2,3-c]acridin-7-one;7H-Pyrano[2,3-c]acridin-7-one,3,12-dihydro-6-methoxy-3,3,12-trimethyl-;3,3,12-Trimethyl-6-methoxy-7,12-dihydro-3H-pyrano[2,3-c]acridine-7-one
CBNumber:
CB71177962
Molecular Formula:
C20H19NO3
Molecular Weight:
321.37
MOL File:
7008-42-6.mol
MSDS File:
SDS
Modify Date:
2023/4/23 13:52:06

Acronine Properties

Melting point 175-176℃
Boiling point 460.13°C (rough estimate)
Density 1.202±0.06 g/cm3 (20 ºC 760 Torr)
refractive index 1.5600 (estimate)
pka -2.43±0.40(Predicted)
Water Solubility 2.7mg/L(25 ºC)
EPA Substance Registry System Acronycine (7008-42-6)

Acronine Chemical Properties,Uses,Production

Uses

Antineoplastic.

Definition

ChEBI: An alkaloid antineoplastic agent isolated from Acronychia baueri.

General Description

Yellow powder.

Air & Water Reactions

Water insoluble.

Reactivity Profile

Amines, like Acronine, are weak chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

Health Hazard

ACUTE/CHRONIC HAZARDS: When heated to decomposition Acronine emits toxic fumes.

Fire Hazard

Flash point data for Acronine are not available. Acronine is probably combustible.

Acronine Preparation Products And Raw materials

Acronine 3,12-Dihydro-6-methoxy-3,3,12-trimethyl-7H-pyrano[2,3-c]acridin-7-one 3,3,12-Trimethyl-6-methoxy-7,12-dihydro-3H-pyrano[2,3-c]acridine-7-one Compound 42339 NSC-403169 NCI-C 01536 Acronycine (Acronine) 7H-Pyrano[2,3-c]acridin-7-one,3,12-dihydro-6-methoxy-3,3,12-trimethyl- 7008-42-6