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Raubasine

Raubasine Structure
CAS No.
483-04-5
Chemical Name:
Raubasine
Synonyms
Tensyl;Sarpan;Vincain;Vincein;Lamuran;Ranitol;RAUBASIN;Vinceine;Vincaine;Raubasil
CBNumber:
CB7129678
Molecular Formula:
C21H24N2O3
Molecular Weight:
352.43
MOL File:
483-04-5.mol
Modify Date:
2024/4/23 16:18:34

Raubasine Properties

Melting point 258°C (rough estimate)
Boiling point 486.04°C (rough estimate)
alpha D20 -60° (c = 0.5 in chloroform); D20 -45° (c = 0.5 in pyridine); D20 -39° (c = 0.25 in methanol)
Density 1.1823 (rough estimate)
refractive index 1.6500 (estimate)
storage temp. 2-8°C
solubility Chloroform (Slightly), Methanol (Slightly, Heated)
form Solid
pka pK1:10.55(+1) (25°C)
color Pale Yellow
optical activity [α]/D -65±3°, c = 1 in chloroform
Water Solubility insoluble in water
BRN 97268
LogP 2.880 (est)
NIST Chemistry Reference Ajmalicine(483-04-5)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H300
Precautionary statements  P264-P270-P301+P310+P330-P405-P501
Hazard Codes  Xn
Risk Statements  25-22
Safety Statements  22-45
RIDADR  1544
WGK Germany  3
RTECS  AX7875000
HazardClass  6.1(b)
PackingGroup  III
NFPA 704
0
2 0

Raubasine price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 41111 Ajmalicine ≥98.0% (HPLC) 483-04-5 10MG ₹5196 2022-06-14 Buy
Sigma-Aldrich(India) 41111 Ajmalicine ≥98.0% (HPLC) 483-04-5 50MG ₹15425.63 2022-06-14 Buy
SRL 19339 Ajmalicine pure, 98% 483-04-5 10mg ₹3540 2022-05-26 Buy
SRL 19339 Ajmalicine pure, 98% 483-04-5 50mg ₹13410 2022-05-26 Buy
Product number Packaging Price Buy
41111 10MG ₹5196 Buy
41111 50MG ₹15425.63 Buy
19339 10mg ₹3540 Buy
19339 50mg ₹13410 Buy

Raubasine Chemical Properties,Uses,Production

Description

Vinca rosea L. yields this alkaloid which crystallizes as colourless needles from MeOH. The base is laevorotatory having a specific rotation of [α]D_620 (MeOH) and forms a crystalline hydrochloride, m.p. 281-3°e. The structure given above has been elucidated from chemical and spectroscopic data.

Uses

Antihypertensive, anti-ischemic (cerebral and peripheral)

Purification Methods

It crystallises from MeOH, EtOH or EtOAc. [Beilstein 27 III/IV 7927.]

References

Janot, Le Men, Cornpt. Rend., 243, 1786 (1956) Shamma, Moss, J. Arner. Chern. Soc., 83, 5038 (1961) Abdurakhsimova, Yuldashev, Yunusov, Khirn. Prir. Soedin., 1,224 (1965)

Raubasine Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 187)Suppliers
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Kothari Phytochemicals and Industries Ltd. +91-9244448844 +91-9331023407 West Bengal, India 18 58 Inquiry
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Indo Phytochem Pharmaceuticals +91-9315656907 +91-9816687908 Himachal Pradesh, India 11 58 Inquiry
Sarv Bio Labs Pvt Ltd +91-9958217221 +91-9875997034 Haryana, India 10 58 Inquiry
CHEMSWORTH +91-261-2397244 New Delhi, India 6707 30 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Sisco Research Laboratories Pvt. Ltd. +91-22-4268 5800 Mumbai, India 4317 58 Inquiry
RAUBASIN RAUBASINE YOHIMBINE, C- , 7-[3-hydroxy-2-(3-hydroxy-1-octenyl)-5-oxocyclopentyl]- 16,17-Didehydro-19alpha-methyloxayohimban-16-carboxylic acid methyl ester 16,17-Didehydro-19-methyloxayohimban-16-carboxylic acid methyl ester 16,17-didehydro-19-methyloxayohimban-16-carboxylicacidmethylester 19-Epiajmalicine 4H-Indolo[2,3-a]pyrano[3,4-g]quinolizine, oxayohimban-16-carboxylic acid deriv. Ajmalicin Alkaloid C Alkaloid F Alkaloid II substanceii Tensyl Tetrahydroserpentine Vincain Vincein Vinceine Vinceinen D-YOHIMBINE ALPHA-YOHIMBIN AJMALICINE AJMALICINE(-YOHIMBINE) AJMALICINE HCl(RG) Ajmalicine (base and/or unspecified salts) (19alpha)-16,17-Didehydro-19-methyloxayohimban-16-carboxylic acid methyl ester Vincaine (19α)-16,17-Didehydro-19-Methyl-oxayohiMban-16-carboxylic Acid Methyl Ester NSC 72133 NSC 95087 TETRAHYDROALSTONINE; AJMALICINE alkaloidc alkaloidf alkaloidii Circolene delta-Yohimbine gamma-Yohimbine Hydrosarpan Isoarteril Lamuran Methyl 19-methyl-16,17-didehydrooxayohimban-16-carboxylate Oxayohimban-16-carboxylic acid, 16,17-didehydro-19-methyl-, methyl ester, (19alpha)- oxayohimban-16-carboxylicacid,16,17-didehydro-19-methyl-,methylester,(19 Py-tetrahydroserpentine Ranitol Raubaserp Raubasil Raumalina Rauvasan Sarpan Substance II Oxayohimban-16-carboxylic acid, 16,17-didehydro-19-methyl-, methylester, (19a)- Raubasine USP/EP/BP (4S,4aR,13bS,14aS)-Methyl 4-methyl-4a,5,7,8,13,13b,14,14a-octahydro-4H-indolo[2,3-a]pyrano[3,4-g]quinolizine-1-carboxylate Vinceine (Raubasine) Ajmalicine pure, 98% Oxayohimban-16-carboxylic acid, 16,17-didehydro-19-methyl-, methyl ester, (19α)-