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ACYL-COENZYME A SYNTHETASE

ACYL-COENZYME A SYNTHETASE Structure
CAS No.
9013-18-7
Chemical Name:
ACYL-COENZYME A SYNTHETASE
Synonyms
C:C&B6;EC 6.2.1.3;Acyl-CoA ligase;Acyl-CoA synthase;Acy-CoA Synthelase;Acyl-CoA Synthetase;Fatty acyl-CoA ligase;Fatty acid thiokinase;Fatty acid CoA ligase;Acyl-coenzyme A ligase
CBNumber:
CB7155341
Molecular Formula:
Molecular Weight:
0
MOL File:
Mol file
Modify Date:
2023/8/18 14:52:35

ACYL-COENZYME A SYNTHETASE Properties

storage temp. -20°C
form powder
color white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08
Signal word  Danger
Hazard statements  H334
Precautionary statements  P261-P285-P304+P341-P342+P311-P501
Safety Statements  24/25
WGK Germany  3
10
HS Code  35079090

ACYL-COENZYME A SYNTHETASE price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) A3352 Acyl-coenzyme A Synthetase from Pseudomonas sp. ≥2?units/mg protein 9013-18-7 1UNIT ₹19547.1 2022-06-14 Buy
Sigma-Aldrich(India) A3352 Acyl-coenzyme A Synthetase from Pseudomonas sp. ≥2?units/mg protein 9013-18-7 10UNITS ₹107692.2 2022-06-14 Buy
Product number Packaging Price Buy
A3352 1UNIT ₹19547.1 Buy
A3352 10UNITS ₹107692.2 Buy

ACYL-COENZYME A SYNTHETASE Chemical Properties,Uses,Production

Chemical Properties

White powder

Uses

Acyl-coenzyme A (coA) synthetase from Pseudomonas sp. has been used:

  • as ligase in the synthesis of mevalonate derivatives of adenosine triphosphate (ATP)
  • in in vitro fatty acylation assays
  • in the synthesis of (14C)Vernoloyl-CoA (Va-CoA),(3) bisphosphonates derivatives of ATP(4) and (3H)Palmitate-CoA

General Description

Acyl-coenzyme A synthetase belongs to adenylate-forming enzymes superfamily. It has a conserved adenosine triphosphate/adenosine monophosphate (ATP/AMP) binding motif.

Purification Methods

Purify the synthase by extraction with sucrose/HCO3 buffer, protamine sulfate precipitation, (NH4)2SO4 (66-65%) fractination (pH 4.35) and a second (NH4)2SO4 (35-60%) fractionation (pH 4.35). It has Km 0.15mM (Vrel 1.0) for octanoate and 0.41mM (Vrel 2.37) for heptanoate. The Km for ATP is 0.5mM, all at pH 9.0 in ethylene glycol buffer at 38o. [Jencks et al. J Biol Chem 204 453 1953, Methods Enzymol 5 467 1962.]

ACYL-COENZYME A SYNTHETASE Preparation Products And Raw materials

Raw materials

Preparation Products

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Acyl-CoA synthase Acyl-coenzyme A ligase Fatty acid CoA ligase Fatty acid thiokinase Fatty acid thiokinase (long chain) Fatty acyl CoA synthetase Fatty acyl-CoA ligase Fatty acyl-coenzyme A synthetase Hexanoyl coenzyme A synthetase Hexanoyl-CoA synthetase EC 6.2.1.3 ACID: COA LIGASE (AMP-FORMING) ACYL-COENZYME A SYNTHETASE Synthetase, acyl coenzyme A ACYL-COENZYME A SYNTHETASE FROM PSEUDO-M ONAS SP., ~2.5U/MG acyl-coenzyme a synthetase from pseudomonas sp. Acyl-coenzyme A Synthetase [>=8 units/mg] Acyl-CoA Synthetase 3-Hydroxyacyl-CoA synthase Acyl-CoA ligase Acy-CoA Synthelase Acyl-CoA Synthetase, ≥8U/mg protein Acyl-CoA synthetase, recombinant Acyl-CoA synthetase from Microorganism Native Pseudomonas fragi Acyl-CoA Synthetase Native Pseudomonas sp. Acyl-coenzyme A Synthetase C:C&B6 ACYL-COENZYME A SYNTHETASE USP/EP/BP Acyl-CoA Synthetase / Acid:CoA ligase acetyl coenzyme A synthetase 9013-18-7 BioChemical Cell Biology Cell Signaling and Neuroscience Enzymes General Metabolic Enzymes A-H General Metabolic Enzymes G Proteins and Cyclic Nucleotides G Protein Function Metabolomics