(+/-)-CGP-12177 HYDROCHLORIDE

(+/-)-CGP-12177 HYDROCHLORIDE Structure
CAS No.
81047-99-6
Chemical Name:
(+/-)-CGP-12177 HYDROCHLORIDE
Synonyms
Tbhpbo;CGP 12177;CGP12177HCl;S(-)-CGP-12177;TOC CGP 12177;(S)-(-)-CGP-12177;CGP 12177 hydochloride;CGP 12177 HYDROCHLORIDE;(+/-)-CGP-12177 HYDROCHLORIDE;4-(3-tert-Butylamino-2-Hydroxypropoxy)benzimidazol-2-One
CBNumber:
CB7157956
Molecular Formula:
C14H21N3O3
Molecular Weight:
279.33
MOL File:
81047-99-6.mol
Modify Date:
2023/4/23 13:52:06

(+/-)-CGP-12177 HYDROCHLORIDE Properties

Melting point >256°C (dec.)
Boiling point 376.3±37.0 °C(Predicted)
Density 1.179
storage temp. Store at RT
solubility DMSO: >10 mg/mL
pka 11.48±0.30(Predicted)
form solid
color white

SAFETY

Risk and Safety Statements

WGK Germany  3

(+/-)-CGP-12177 HYDROCHLORIDE Chemical Properties,Uses,Production

Definition

ChEBI: A benzimidazole that is benzimidazol-2-one substituted at position 4 by a 3-(tert-butylamino)-2-hydroxypropoxy group.

Biological Activity

Partial agonist at β 3 -adrenoceptors. β 1 - and β 2 -adrenoceptor antagonist (K i values are 0.9, 4 and 88 nM for β 1 , β 2 and β 3 receptors respectively).

(+/-)-CGP-12177 HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

(+/-)-CGP-12177 HYDROCHLORIDE Suppliers

Global( 23)Suppliers
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(+/-)-CGP-12177 HYDROCHLORIDE CGP 12177 HYDROCHLORIDE 4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE HYDROCHLORIDE CGP12177HCl CGP 12177 hydochloride CGP 12177 4-(3-tert-Butylamino-2-Hydroxypropoxy)benzimidazol-2-One 4-(3-tert-Butylamino-2-hydroxypropoxy)-1H-benzimidazol-2(3H)-one (S)-(-)-CGP-12177 1,3-Dihydro-4-[(S)-3-(tert-butylamino)-2-hydroxypropoxy]-2H-benzimidazol-2-one 4-[[(2S)-2-Hydroxy-3-(tert-butylamino)propyl]oxy]-1H-benzimidazole-2(3H)-one S(-)-CGP-12177 TOC CGP 12177 2H-Benzimidazol-2-one, 4-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-1,3-dihydro- Tbhpbo 4-[3-[(tert-butyl)amino]-2-hydroxypropoxy]-1,3-dihydro-2H-benzimidazol-2-one 4-[3-(tert-butylamino)-2-hydroxypropoxy]-1,3-dihydrobenzimidazol-2-one 81047-99-6 C14H21N3O3HCl Adrenoceptor