ChemicalBook > Product Catalog >Biochemical Engineering >Polypeptide >H-CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH
H-CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH
- CAS No.
- 117399-93-6
- Chemical Name:
- H-CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH
- Synonyms
- et-3;EDN3;WS4B;HSCR4;PPET3;human,rat;ET-3, HUMAN;ENDOTHELIN-3;CAS:117399-93-6;Rat endothelin-3
- CBNumber:
- CB7181630
- Molecular Formula:
- C121H168N26O33S4
- Molecular Weight:
- 2643.04
- MOL File:
- 117399-93-6.mol
- Modify Date:
- 2025/6/18 16:39:18
| Density | 1.285±0.06 g/cm3(Predicted) |
|---|---|
| storage temp. | −20°C |
| solubility | 5% acetic acid: 0.5mg/mL |
| form | powder |
| color | white |
| biological source | rabbit |
| Water Solubility | Soluble to 1 mg/ml in water |
| Sequence | Cys-Thr-Cys-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys-Val-Tyr-Tyr-Cys-His-Leu-Asp-Ile-Ile-Trp(Disulfide bridge: Cys1-Cys15, Cys3-Cys11) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H300+H330 |
| Precautionary statements | P301+P310+P330-P304+P340+P310 |
| Safety Statements | 22 |
| WGK Germany | 3 |
| F | 3-10 |
H-CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | E9137 | Endothelin 3 human, rat ≥97% (HPLC), powder | 117399-93-6 | 10μG | ₹12632.78 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | E9137 | Endothelin 3 human, rat ≥97% (HPLC), powder | 117399-93-6 | 50μG | ₹36014.78 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | E9137 | Endothelin 3 human, rat ≥97% (HPLC), powder | 117399-93-6 | 0.1MG | ₹62319.53 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 05-23-3801 | Endothelin 3, Human and Rat - CAS 117399-93-6 - Calbiochem Attenuates thrombin-evoked aggregation of human platelets. | 117399-93-6 | .5MG | ₹47630 | 2022-06-14 | Buy |
H-CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH Chemical Properties,Uses,Production
Uses
Endothelin 3 human, rat has been used for culturing neural tube explant culture, and the pharmacological study of endothelin receptors.
General Description
Endothelin 3 (ET3) belongs to endothelin peptide family, which includes three members, ET-1, -2 and -3. These are 21-amino acid peptides, which are synthesized as precursors. They are converted to biologically active peptides, after being cleaved by proteases. There are two endothelin receptors called ETRA and ETRB, and ET3 binds to ETRB. It is localized to human intestine and colon.
Biochem/physiol Actions
Endothelin 3 (ET3) is a vasoconstrictor that acts in a paracrine and autocrine manner, and in intestinal lamina propria causes the degranulation of mast cells. It results in the release of ions from intestinal epithelial cells. In acute and chronic intestinal inflammation, it is overexpressed. It is also up-regulated in colon carcinoma, where it supports cell proliferation and survival. It might be involved in colon homeostasis, and is essential for the survival and proliferation of goblet cells. In mice, it is essential for the development of pigment cells derived from neural crest (NC). Its expression is de-regulated in metastatic melanoma.
H-CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH Preparation Products And Raw materials
Raw materials
Preparation Products
H-CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH Suppliers
Global( 134)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | China | 10406 | 58 | Inquiry |
| BOC Sciences | +1-631-485-4226 | United States | 19552 | 58 | Inquiry |
| Cellmano Biotech Limited | 0551-65326643 18156095617 | China | 995 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29804 | 58 | Inquiry |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 22483 | 58 | Inquiry |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 | China | 10473 | 58 | Inquiry |
| Alfa Chemistry | +1-5166625404; | United States | 20405 | 58 | Inquiry |
| Chengdu Youngshe Chemical Co., Ltd. | +8618108235634 | China | 2345 | 58 | Inquiry |
| TargetMol Chemicals Inc. | United States | 38828 | 58 | Inquiry | |
| Hebei Miaoyin Technology Co.,Ltd | +852-852-95427495 +85295427495 | China | 3512 | 58 | Inquiry |
117399-93-6(H-CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH)Related Search:
H-CYS-SER-CYS-SER-SER-TRP-LEU-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH
IRL-1038
Endothelin-1 (human, porcine)
BIG ET-1 (1-38) (HUMAN)
ENDOTHELIN (16-21)
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1of4
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ENDOTHELIN-III, HUMAN, RAT
ENDOTHELIN-3
ENDOTHELIN-3, HUMAN
ENDOTHELIN 3, HUMAN AND RAT
ENDOTHELIN-3 (HUMAN, MOUSE, RABBIT, RAT)
ENDOTHELIN-3 (HUMAN) (PORCINE, RAT, RABBIT)
ENDOTHELIN 3 HUMAN, RAT
ENDOTHELIN-3 (HUMAN, RAT, PIG)
ENDOTHELIN-3 (HUMAN, RAT, PORCINE, RABBIT)
CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP
CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP HUMAN, RAT, PORCINE, RABBIT
CTCFTYKDKECVYYCHLDIIW
CTCFTYKDKECVYYCHLDIIW (DISULFIDE BRIDGE: 1-15 AND 3-11)
H-CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH
H-CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH (DISULFIDE BRIDGE: 1-15 AND 3-11)
ET-3, HUMAN
ET-3, HUMAN AND RAT
ET-3 (HUMAN, MOUSE, RABBIT, RAT)
ET-3 (HUMAN, RAT)
ET-3 (HUMAN, RAT, PIG)
human,rat
et-3
M.W. 2643.04 C121H168N26O33S4
Endothelin 3【canine】
Endothelin 3【rabbit】
Endothelin 3【rat】
CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR- TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP(DISULFIDE BRIDGE:CYS1-CYS15, CYS3-CYS11)
CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP: CTCFTYKDKECVYYCHLDIIW DISULFIDE BRIDGES CYS1-CYS15, CYS3-CYS11
Endothelin-3 (huMan, Mouse, rabbit, rat)
ET-3 (huMan, Mouse, rabbit, rat)
Cys-Thr-Cys-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys-Val-Tyr-Tyr-Cys-His-Leu-Asp-Ile-Ile-Trp (Disulfide bridges Cys1-Cys15 and Cys3-Cys11)
Endothelin 3 huMan, ratEndothelin
Endothelin 3 (huMan)(9CI)
Anti-EDN3 antibody produced in rabbit
EDN3
HSCR4
ANTI-EDN3 (C-TERM) antibody produced in rabbit
19: PN: WO2007112069 SEQID: 10 claimed protein
33,34,49,50-Tetrathia-2,5,8,11,14,17,20,23,26,29,37,40,43,46-tetradecaazabicyclo[23.22.4]henpentacontane, cyclic peptide deriv.
Endothelin 3 (mouse intestine)
Human endothelin-3
Rat endothelin-3
ENDOTHELIN 3, HUMAN, RAT, 50 UG*
Endothelin 3, human, rat, ≥97% (HPLC), powder
Endothelin 3, Human and Rat - CAS 117399-93-6 - Calbiochem
Endothelin 3 (Rat,Human)
L-Tryptophan, L-cysteinyl-L-threonyl-L-cysteinyl-L-phenylalanyl-L-threonyl-L-tyrosyl-L-lysyl-L-α-aspartyl-L-lysyl-L-α-glutamyl-L-cysteinyl-L-valyl-L-tyrosyl-L-tyrosyl-L-cysteinyl-L-histidyl-L-leucyl-L-α-aspartyl-L-isoleucyl-L-isoleucyl-, cyclic (1→15),(3→11)-bis(disulfide)
H-CYS-THR-CYS-PHE-THR-TYR-LYS-ASP-LYS-GLU-CYS-VAL-TYR-TYR-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH USP/EP/BP
Endothelin 3 human, rat (TFA)
Human endothelin-3/Rat endothelin-3
CAS:117399-93-6
Endothelin 3, human, rat, mouse, rabbit
(3S)-3-[[(2S)-2-[[(2S)-2-[[(1R,4S,7S,10S,13S,16S,19S,22S,25R,28S,31R,36R,39S,42S,45S)-31-amino-7,13-bis(4-aminobutyl)-22-benzyl-4-(2 -carboxyethyl)-10-(carboxymethyl)-19,28-bis[(1R)-1-hydroxyethyl]-16,39,42-tris[(4-hydroxyphenyl)methyl]-3,6,9,12,15,18,21,
PPET3
WS4B
117399-93-6
C121H168N26O33S4
Agonist
BioChemical